Granata was among the leading U.S. researchers on
biomechanics and movement dynamics in
cerebral palsy, in his work with the Musculoskeletal Biomechanics Laboratory at Virginia Tech. His research focused on muscle and reflex control and its relation to legged
robotics, neuromuscular control of musculoskeletal movement, biomechanical stability and muscle dynamics, control of low-back pain, and computer simulation and clinical interpretation of pathologic walking and running. Professor Granata was recruited to the Department of Engineering Science and Mechanics to continue his distinguished teaching and research. In particular, he developed innovative methods to quantify low back stability that are considered cutting edge by other leaders in the field. He served as mentor for numerous students and junior professors. When Granata was promoted to the rank of professor, one of these professors conveyed, "Countless times he has provided me with valuable guidance on research-related matters such as student advising, experimental issues, and manuscript preparation." While focusing primarily on research into
cerebral palsy, biomimetric robotics and biomechanics, Granata helped develop mobility aids for the elderly such as the MARC Robotic Walker. The MARC Walker is named for the Medical Automation Research Center at the University of Virginia, where Granata had taught until January 10, 2003. He presented a paper on the elderly walker at the 2003 International Conference on Robots and Systems in
Las Vegas. Granata was an associate professor at Virginia Tech and in 2005, he achieved the honor of Virginia Tech College of Engineering Faculty Fellow. In 2006, he was awarded the Dean's Award for Excellence in Research for his work on lower back pain. In announcing the Dean's Award given to Granata, Virginia Tech stated he had "established a major research program, developing innovative methods to quantify low back stability that are considered cutting edge." He was additionally honored as the Virginia Tech Scholar of the Week for his published work concerning lower back pain. His friends and colleagues at Virginia Tech called him "a man with a sharp intellect who answered a call to serve the cause of scholarship and higher education". At the time of his death, he was awaiting publication of four more articles in his name. ==Personal life==