WNBA At the
2018 WNBA draft, Nurse was drafted by the
New York Liberty in the first round as the tenth overall pick. Nurse joined the Liberty alongside players such as
Tina Charles and
Epiphanny Prince. Nurse made her WNBA debut on May 20, 2018, scoring 17 points in an eventual 80–76 loss to the
Chicago Sky. In June 2018, Nurse scored 34 points, a season-high amongst WNBA rookies, in the Liberty's 87–81 overtime victory over the Indiana Fever. In July 2019, Nurse was named as a starter for the
WNBA All-Star Game for the first time in her career. Her selection made her just the third Canadian to play in the All-Star Game. Nurse was selected by and joined
Team Delle Donne for the game. Nurse also participated in the Three-Point Contest but was one of four competitors eliminated in the first round. Nurse was traded to the
Phoenix Mercury with
Megan Walker by the Liberty for the
2021 season for the Mercury's
2021 and
2022 first-round picks. Nurse tore her
ACL in Game 4 of the WNBA semifinals against the
Aces, which led to her to missing the remaining postseason games. The Mercury lost in the finals against the
Chicago Sky. On February 5, 2022, the Mercury announced that they had re-signed Nurse for the
2022 season. Nurse's injury caused her to miss the entire 2022 season. On January 31, 2024, Nurse was traded by the
Seattle Storm to the
Los Angeles Sparks alongside the
2024 WNBA draft first-round pick (fourth overall) for the Sparks' 2026 first-round pick. On February 4, 2025, Nurse signed with the Chicago Sky. In 2025, Nurse averaged 7.8 points and 2.3 rebounds per game. In a game against the
Golden State Valkyries on August 1, she notched a career-high seven assists. On April 14, 2026, Nurse signed with the
expansion Toronto Tempo, she became the first Canadian player to sign for the first Canadian team in the WNBA.
Athletes Unlimited Nurse made her
Athletes Unlimited Pro Basketball debut during the 2025 season, finishing ninth on the final leaderboard with 4,254 points. She averaged 15.8 points and 5.4 rebounds per game, earned three Game MVP awards, and served as a team captain during Week Two. In 2026, Nurse returned to
Athletes Unlimited Pro Basketball for her second season with the league. ==National team career==