Miami Dolphins 2012 season Miller was selected by the
Miami Dolphins in the fourth round of the
2012 NFL draft, 97th overall on April 28, 2012. On June 1, 2012, Miller signed a 4-year, $2.58 million contract, including a $480,000 signing bonus. As a rookie, Miller shared the backfield with
Reggie Bush and
Daniel Thomas. On September 16, he made his NFL debut running for 65 yards on a season-high 10 carries and a touchdown against the
Oakland Raiders. On December 23, Miller ran for a season-high 73 yards on 10 carries against the
Buffalo Bills. In the 2012 season, Miller rushed for 250 yards and a touchdown.
2013 season After the departure of Reggie Bush, Miller became the main running back on the team and continued to share time with Daniel Thomas. In Week 9, against the
Cincinnati Bengals, Miller had 16 carries for 105 yards in the 22–20 victory. Overall, he finished the 2013 season with 177 carries for 709 rushing yards and two rushing touchdowns to go along with 26 receptions for 170 receiving yards.
2014 season , 2014 Coming into the 2014 season, Miller was the main running back with a backfield that consisted of him, Thomas, Damien Williams, and
Knowshon Moreno. In Week 4, against the
Oakland Raiders, he had his first game with two rushing touchdowns in the 38–14 victory. In the Week 17 finale, Miller had a career-high 178 rushing yards and a rushing touchdown in the 37–24 loss to the
New York Jets. Miller's rushing touchdown in the game went for 97 yards, the longest rushing play in franchise history. In the 2014 season, Miller finished with 216 carries for 1,099 rushing yards and eight rushing touchdowns to go along with 38 receptions for 275 receiving yards and one receiving touchdown.
2015 season In Week 7, against the
Houston Texans, Miller had 175 rushing yards, one rushing touchdown, 61 receiving yards, and one receiving touchdown in the 44–26 victory. In Week 9, against the
Buffalo Bills, he had 141 scrimmage yards in the 33–17 loss. In Week 14, against the
New York Giants, he had this third career game with two rushing touchdowns. In the 2015 season, Miller finished with 194 carries for 872 yards and eight rushing touchdowns to go along with 47 receptions for a career-high 397 yards and two receiving touchdowns.
Houston Texans On March 9, 2016, Miller signed a four-year deal with the
Houston Texans worth $26 million with $14 million guaranteed. This contract was the sixth highest among running backs. In the 2016 season, Miller rushed for 1,073 yards and five rushing touchdowns to go along with 31 receptions for 188 receiving yards and one receiving touchdown. He had four games going over the 100-rushing yards mark. The Texans qualified for the playoffs in the 2016 season. In the
Wild Card Round against the
Oakland Raiders, Miller had 31 carries for 73 yards and a rushing touchdown in the 27–14 victory. In the
Divisional Round against the New England Patriots, he finished with 19 carries for 74 yards and four receptions for 15 yards in the 34–16 loss.
2017 season In Week 4, against the
Tennessee Titans, Miller had a rushing and a receiving touchdown in the 57–14 victory. In Week 8, against the
Seattle Seahawks, he had another game with a rushing touchdown and a receiving touchdown. In the 2017 season, Miller finished with 238 carries for 888 rushing yards, three rushing touchdowns, 36 receptions, 327 receiving yards, and three receiving touchdowns.
2018 season In the season opener against the
New England Patriots, Miller ran for 98 yards and caught a pass for 11 yards in the 20–27 loss. On September 23, Miller scored his first touchdown of the season, bringing in a touchdown catch on the final play of the game against the
New York Giants. On October 21, Miller rushed for 100 yards and a touchdown on 22 carries against the
Jacksonville Jaguars. This touchdown was his eighth touchdown on the ground as a Texan, moving past quarterback
David Carr into seventh-most in franchise history. The next week, Miller rushed for 133 yards and a touchdown against the
Miami Dolphins, included as well was a 58-yard run. His back-to-back 100-yard games were his first time as a Texan, the last time this was accomplished by a Texan was by
Arian Foster in 2014. After this game, Foster surpassed 100 yards for the sixth time as a Texan, passing
Steve Slaton,
Ben Tate, and teammate
Alfred Blue into third most in franchise history. After running up 86 yards against the
Washington Redskins, he would follow that game with 162 yards and a touchdown against the
Tennessee Titans, including a 97-yard touchdown run. His touchdown run is the longest play in franchise history, and was the longest touchdown run in the NFL since he did it in 2014, becoming the only player in NFL history with two touchdown runs over 95 yards in a career. Overall, Miller finished the 2018 season with 973 rushing yards, five rushing touchdowns, 25 receptions, 163 receiving yards, and a receiving touchdown. The Texans finished atop the AFC South and earned the #3-seed for the AFC Playoffs. In the
Wild Card Round against the
Indianapolis Colts, he had eight receptions for 63 yards in the 21–7 loss. He also rushed for 18 yards on five carries. Miller earned a Pro Bowl nomination for his 2018 season.
2019 season During the team's third preseason game against the
Dallas Cowboys, Miller tore his ACL, prematurely ending his season. He was placed on injured reserve on August 26, 2019.
New England Patriots On August 13, 2020, Miller signed with the
New England Patriots. He was placed on the active/
physically unable to perform list after signing. He was activated on August 31, 2020. Miller was released from the Patriots on September 5, 2020.
Chicago Bears Miller was signed to the
Chicago Bears' practice squad on October 5, 2020. The move reunited him with offensive coordinator
Bill Lazor and running backs coach
Charles London, whom he respectively played under in Miami and Houston, respectively. He was elevated to the active roster on November 16 for the team's Week 10 game against the
Minnesota Vikings, and reverted to the practice squad after the game, in which he recorded two catches for six yards and had no rushing attempts.
Washington Football Team On December 17, 2020, Miller was signed by the
Washington Football Team off the Bears' practice squad. He re-signed with the team on March 29, 2021, and was released on August 15, 2021.
New Orleans Saints On October 19, 2021, the
New Orleans Saints signed Miller to their practice squad. He was released on November 16, 2021. ==Career statistics==