The game received mixed reviews, according to
review aggregator Metacritic. Shaun Musgrave of
TouchArcade gave the game five out of five stars, praising the series's smooth transition to mobile platforms, the "outstanding" presentation, the story and the puzzles.
Game Informers Kyle Hilliard considered Katrielle a more enjoyable protagonist than her father. However, he had issue with the game's narrative structure, considering the standalone nature of the cases to cause the finale to "fall flat", as well as the puzzles, which he considered to overall be mediocre, and to have some "frankly stupid solutions". Daan Koopman of
Nintendo World Report gave the 3DS version of the game a 7.5 out of 10. He praised the game's colorful presentation, as well as the gameplay being as "entertaining as ever", although he felt that the puzzles were too easy compared to the prior entries. He also noted that the ability for the player to return to prior cases offered much extra content to players and helped the world of the game feel alive. He, however, was underwhelmed by the game's story due to its overarching plot being "sorely lacking", and felt that the "conclusion came out of left field".
Adventure Gamerss Jack Allin felt as though the case structure made for accessible mobile and casual gaming, and was positive towards the "pitch-perfect voice acting", as well as the visuals, and the high quantity of puzzles. However, he considered there to be "too many duds in the puzzle pile", and that the backgrounds, characters, and music got repetitive and tiresome. He also felt that the "simplified case focus makes the story entirely forgettable". He gave the game 3 out of 5 stars. On the other hand, despite the simplified narrative style,
GameCentral for
Metro still considered there to be little fundamental change compared to the prior titles in the series, which offered very few new ideas. They also felt as though, "despite being its natural home, the 3DS offers no real advantage", pointing out the lack of 3D effects, which were present in previous titles. They also noted the prices for both versions, specifically that an £18 price tag was something that "never worked" for mobile games, although they considered it to be "good value for money", especially given that free daily puzzles are being promised as
downloadable content for up to a year after release. On the other hand, they considered the 3DS version being more than twice as expensive as the mobile version to be a negative, even with the costume sets, which were paid for DLC in the mobile version, being bundled into the retail release. ''Layton's Mystery Journey'' was the 29th best selling video game in the United Kingdom during the Nintendo 3DS version's European debut week, and the second best selling Nintendo 3DS game in the region after ''
Mario & Luigi: Superstar Saga + Bowser's Minions''. The game was nominated for "Game, Franchise Family" at the National Academy of Video Game Trade Reviewers Awards. == Notes ==