Leonello was one of three illegitimate sons of
Niccolò d'Este III and Stella de' Tolomei. He received a military education under the
condottiero Braccio da Montone, and was tutored by
Guarino Veronese, later appointed professor at the
University of Ferrara, who also instructed him on the traits of a desirable ruler and how to govern. In 1425, after the execution of his elder brother
Ugo Aldobrandino, he was the sole heir of Niccolò. In 1435, he married
Margherita Gonzaga on 6 February and was recognized as legitimate son by
Pope Martin V. Margherita, who died in 1439, gave birth to a child, Niccolò, in 1438, who is also known as Niccolò di Leonello to avoid confusion with his grandfather Niccolò d'Este III. Niccolò the son died in 1476. In late December 1441, Leonello succeeded to his father's possessions after his death in northern Italy. Coming from a strong academic background, Leonello brought significant unprecedented economic, political, and cultural changes to
Ferrara right after he took over from Niccolò III. In May 1444, Leonello married Mary of Aragon who was at the age of 19, an illegitimate daughter of King
Alfonso V of Naples. The marriage was a political one. To ensure the political stability within Ferrara, Leonello remained neutral in the political affairs between
Milan and
Venice. However, Leonello had a much broader picture for Ferrara, expanding its authority and power in its area. After the death of Margherita Gonzaga, Leonello saw the opportunity of forming alliances with neighboring regions through kinship to strengthen its power. The victory of Alfonso V in Naples, the father of Mary of Aragon, acted as a catalyst for such a diplomatic marriage for Leonello and an opportunity for Ferrara. Not much progress was made during the rule of Niccolò III as he focused more on political matters and economic prosperity within Ferrara. Leonello was a skilled politician and was responsible for the construction of the first hospital of Ferrara. But he distinguished himself chiefly as a man of culture.
Leon Battista Alberti wrote his
De Re Aedificatoria at Leonello's commission, and at the Ferrarese court there worked artists such as
Pisanello,
Iacopo Bellini,
Giovanni da Oriolo,
Andrea Mantegna,
Piero della Francesca and the Netherlandish
Rogier van der Weyden. His personal
breviary was sold in a fragmented state in 1958 by Baron Llangattock at
Christie's. It has since then been known as the Llangattock breviary. It was created under the artistic direction of Giorgio d´Alemagna and painters like Matteo De Pasti and Jacopo Magnanimo contributed to it. Leaves from it are in the collections of museums such as the
Louvre in Paris, the
Danish National Library, and several private collections. During his rule, the University of Ferrara gained a European prestige. Leonello died in 1450, aged 43. He was succeeded by
Borso d'Este, his father's illegitimate son. ==Family background and history==