Reinhart starred in the television pilot for
Scientastic! (2010) and guest starred on the television series
Law & Order: Special Victims Unit (2011). She also starred in the films
Lilith (2011),
Not Waving But Drowning (2012),
The Kings of Summer (2013),
Gibsonburg (2013), ''
Forever's End (2013), Miss Stevens (2016), and The Good Neighbor'' (2016). On February 9, 2016, Reinhart was cast as
Betty Cooper in
the CW's
teen drama television series
Riverdale, based on the characters of
Archie Comics. Series creator
Roberto Aguirre-Sacasa originally sought out
Kiernan Shipka for the role after seeing her work in
Mad Men. Reinhart auditioned twice for the role, first sending in an audition tape from her North Carolina home before appearing in person a month later. The series premiered on January 26, 2017, and in February 2021, it was renewed for a sixth season. Previously, Reinhart worked on the
Fox sitcom
Surviving Jack. In 2017, Reinhart was cast in
Galveston, based on
Nic Pizzolatto's 2010 novel of the same name. In the film, directed by
Mélanie Laurent, Reinhart plays Tiffany, who was placed for adoption as a child. The film premiered at
South by Southwest on March 10, 2018, and received a
limited theatrical release through
RLJE Films on October 19, 2018.
Galveston received mixed critical reviews and grossed only $190,320 at the box office. Reinhart joined the cast of
Lorene Scafaria's
Hustlers in March 2019. Reinhart played Annabelle, "the baby of the group," a former
stripper who joins Ramona and her crew in drugging and robbing their
Wall Street clientele. Reinhart described her character's aesthetic as "slutty
Hannah Montana." A running gag shows Annabelle vomiting in times of stress, and the fake vomit was made of
animal crackers and
Sprite.
Hustlers premiered at the
Toronto International Film Festival on September 7, 2019, and was theatrically released in the United States the next week. The film received positive critical reviews and grossed $157.6million worldwide. The same year, Reinhart made a
cameo appearance during the
mid-credits scene of
Elizabeth Banks' ''
Charlie's Angels'' (2019). In June 2019, it was announced that Reinhart would star as the female lead of
Amazon Studios' romantic drama film
Chemical Hearts, written and directed by
Richard Tanne and based on the 2016
Krystal Sutherland novel
Our Chemical Hearts. Reinhart played Grace Town, a physically disabled high school senior who falls in love with school newspaper writer Henry Page. In addition to starring,
Chemical Hearts was Reinhart's first
executive producer credit. The film was released on August 21, 2020, on
Amazon Prime Video and received mixed reviews. In May 2020, Reinhart voiced Bella-Ella, "a ... snooty rich [girl]" in the
Simpsons episode "
The Hateful Eight-Year-Olds". In March 2021, it was announced that Reinhart would star in
Wanuri Kahiu's
Look Both Ways as Natalie, a college student whose life diverges into two parallel realities on the eve of her college graduation. In one reality, she becomes pregnant and must navigate motherhood as a young adult; in the other, she moves to LA to pursue her career. In addition to starring in the film,
Look Both Ways was Reinhart's second executive producer credit. In June 2021, Reinhart's production company, Small Victory Productions, signed a deal with Amazon Studios. Small Victory Productions will develop original and adapted content for film and television with a focus on modern, young adult content that celebrates diversity and inclusivity, as well as supporting new voices. ==Other ventures==