Margaret was born at
Farleigh Castle in
Somerset. and his wife
Isabel Neville. George was a son of
Richard of York, 3rd Duke of York, and a brother of both
Edward IV and
Richard III. Warwick was killed fighting against Margaret's uncles at the
Battle of Barnet. Her father, already
Duke of Clarence, was then created
Earl of Salisbury and of Warwick. Edward IV declared that Margaret's younger brother,
Edward, should be known as
Earl of Warwick, but only as a courtesy title, and no peerage was ever created for him. She was most likely named after her paternal aunt
Margaret of York, Duchess of Burgundy. Isabel died suddenly on 22 December 1476, when Margaret was only three years old. The death of his wife led Clarence to believe that her lady-in-waiting and midwife,
Ankarette Twynho, and a servant, had poisoned her and his son with a "venomous drink of ale". He had them brought to trial, found guilty and executed on very slim evidence by a rigged court in April 1477. His grief over his wife's death, and the midwife having been a distant cousin of the Woodvilles, suggested by his sister-in-law
Elizabeth Woodville, made him distance himself from his brother, Edward IV. The Duke of Clarence plotted against Edward IV, and in February 1478 was attainted and executed for treason. His lands and titles were thereby forfeited. Edward IV died in 1483 when Margaret was ten. The following year, the late King's marriage was declared invalid by the statute
Titulus Regius, making his children illegitimate. As Margaret and her brother, Edward, were debarred from the throne by their father's attainder, their uncle,
Richard, Duke of Gloucester, became King Richard III in 1483. He reinforced young Margaret and Edward's exclusion from the line of succession, and married
Anne Neville, Margaret's maternal aunt. and as young Edward was the last male Plantagenet and a potential
House of York claimant, he was moved to the
Tower of London in 1485. Edward was briefly displayed in public at
St Paul's Cathedral in 1487 in response to the presentation of the impostor
Lambert Simnel as the "Earl of Warwick" to the Irish lords. His lands and titles were confiscated. == Marriage ==