Academic Mazzucato was Professor of Economics of Innovation and Public Value at
University College London, where she founded the UCL Institute for Innovation and Public Purpose (IIPP) in 2017 to "explore how the public, private and third sector can work together in new and dynamic ways to drive innovation in order to tackle societal and technological challenges and shape and create new markets", building on Mazzucato's work on
The Entrepreneurial State. Her career began in 1995 as an
adjunct professor of economics at
New York University until 1997. She taught at the
University of Denver between 1997 and 1999. Between 1998 and 1999 she was a post-doctoral Marie Curie Research Fellow at the
London Business School where she worked closely with
Paul Geroski. She joined
The Open University in 1999 as a lecturer and became a full professor in 2005, where she founded their Innovation, Knowledge and Development research centre. From 2008 to 2010 she was a visiting professor at
Bocconi University. Between 2011 and 2017, she was the RM Phillips Chair in the Economics of Innovation at the
University of Sussex before moving to
University College London in 2017. In 2024 she co-founded the Strategic Economics Alliance, a global network amplifying the voices of female economists from the Global South in promoting new economic theory.
Economic advisory Mazzucato has been active in advising governments on innovation, industrial strategy and growth policies. In 2019, South African President
Cyril Ramaphosa appointed Mazzucato to be a member of his Economic Advisory Council, a position where she remains active in providing recommendations for building sustainable and inclusive development. Since 2020, Mazzucato has been a member of the Innovation Expert Group at the United Kingdom
Department of Business, Energy and Industrial Strategy and a member international advisory panel of Vinnova, Sweden's innovation agency. In 2020, Italian Prime Minister Giuseppe Conte appointed Mazzucato as a Special Advisor on economic policy and made her Italy's representative economist on the G7 Panel on Economic Resilience which advised the G7 leaders at the 2021 G7 Summit in Cornwall, UK. She is currently a member of the Council of Economic Advisors to the Scottish Government, a role she has held since 2015. She worked closely with the Scottish Government and First Minister in establishing the Scottish National Investment Bank in 2018. Between 2015 and 2016, she served on the
British Labour Party's Economic Advisory Committee providing advice to the Shadow Cabinet. As well as national governments, Mazzucato has also served as an economic advisor to international institutions, including the
World Economic Forum, the
European Commission, the
World Health Organization, the
OECD, and the
United Nations Department of Economic and Social Affairs. From 2017 to 2021, Mazzucato sat on the United Nations Sustainable Development Solutions Network Leadership Council. She was a member of the
European Commission's Task Force on Public Sector Innovation and their expert group on Innovation for Growth (RISE). From 2018-2019, she was Special Advisor to the European Commission's Commissioner for Research, Science and Innovation,
Carlos Moedas. In 2020,
Tedros Adhanom Ghebreyesus, the Director-General of the World Health Organization, appointed Mazzucato as Chair of the
World Health Organization's Council on the Economics of Health for All. From 2022 to 2023, she served on the
European Space Agency’s High-Level Advisory Group on Human and Robotic Space Exploration for Europe. Between 2022 and 2024 she co-chaired the OECD’s Global Commission on the Economics of Water with
Johan Rockström,
Ngozi Okonjo-Iweala and
Tharman Shanmugaratnam. In 2024, Brazilian president
Lula Da Silva appointed her co-chair of the Group of Experts on the G20 Taskforce on a Global Mobilization against Climate Change with Vera Songwe. Mazzucato also served on the United Nation's High-Level Advisory Board on Economic and Social Affairs, the OECD High-Level Advisory Panel on Climate and Economic, the United Nation's Sustainable Development Solutions Network Leadership Council, the United Nation's Committee for Development Policy and the Commission for Universal Health convened by
Chatham House. In addition to formal appointments, Mazzucato and the UCL Institute for Innovation and Public Purpose have advised several government administrations on innovation policy and
green growth in the United States, Brazil, Colombia and Barbados. Lessons from this work were shared on the IIPP report
Mission-oriented industrial strategy: global insights, published in 2024. Mazzucato has authored a number of policy reports, including
Mission-Oriented Research & Innovation in the European Union, followed by the report
Governing Missions in the European Union, which directly informed the EU's
Horizon Europe research and innovation programme, and
Transformational Change in Latin America and the Caribbean for
ECLAC. Other relevant reports include the Global Commission on the Economics of Water Final Report on valuing the hydrological cycle as a global common good, and the report
A green and just planet, authored by the G20 TF‑CLIMA Group of Experts, both published in 2024. == Research ==