Originally from Dilbeek, Marie Detruyer started playing football at the age of five at Verbroedering Beersel-Drogenbos. When she was 10 years old, she took part in a training session at the Voetbalacademie-Net in the Osbroek park in Aalst with some teammates from Verbroedering Beersel-Drogenbos. It was following this training that she was spotted by Michaël De Meyst, former Eendracht Aalst player and youth coach. Impressed by what she could do with a ball, she was used in videos to show technical exercises. De Meyst contacted his former club in Aalst to take her on, and despite having a policy of not playing girls, took her in for a training session. Impressed, the club was immediately convinced of her potential. This is how Marie becomes the first girl to play in the boys' teams of Eendracht. After a year with the Gent youth side, Detruyer moved to Oud-Heverlee Leuven, and during her first season with the club, was voted twice player of the month (October 2019 and November 2021). During this 2021-22 season, the Louvanistes finished in second place, behind RSC Anderlecht despite a 1-0 victory for their team against the reigning champion Anderlecht. In May 2022, she was nominated for the “Pro Footballer” of the year trophy alongside
Tessa Wullaert from RSC Anderlecht and
Marie Minnaert from
Club YLA, the first set of two consecutive seasons she would be nominated without success. ==International career==