In 1900, before beginning her scientific education, Lebour began her research career with a paper on land and freshwater
molluscs in
Northumberland. While studying for her master's degree, Lebour was on staff at
Durham University. From 1906 to 1909, she was a demonstrator in the Department of Zoology at the
University of Leeds and from 1909 to 1915 she was also an assistant
lecturer. Lebour's professional research career was entirely conducted at the
Marine Biological Association's Laboratory at
Plymouth, where she joined the research staff in 1915. She was a full staff member there until 1946, then an honorary staff member until she could no longer conduct research due to health problems, in 1964. Lebour retired in 1945 at the age of 70, but continued to work into the laboratory and publish until she was 88 and her failing vision prevented her from working at the microscope. == Honours, death and legacy ==