Lousteau was the first minister of economy of
Cristina Fernández de Kirchner. There was a dispute in the cabinet at the time between
Julio de Vido,
Ricardo Jaime and
Guillermo Moreno, and
Alberto Fernández,
Graciela Ocaña,
Jorge Taiana and
Carlos Tomada. Lousteau sided with Alberto Fernández, as he did not share the economic views of De Vido and Moreno. Fernández had promised him that both of them would be removed from government in a short time. Lousteau wrote a report for the president on the figures of the national economy, praising several aspects of the tenure of
Néstor Kirchner, but warning about the growing
inflation. This report was dismissed by Néstor Kirchner, who did not have an actual office but remained an influential figure. He also proposed to gradually reduce the subsidies to energy consumption, to eventually abandon the
fixed price system established during the 2001 crisis. Cristina Kirchner did not support his proposal. The salient feature of his tenure was the controversy surrounding his decision to increase soybean export taxes, which were previously fixed at 35%, and to have them fluctuate in line with global prices for the crop. This has been claimed as the major cause of the
protests in the Argentine countryside which took place in early 2008. Lousteau was heavily involved in talks with farmers' leaders but was later sidelined. Lousteau was rumored as early as two months into his tenure to have declared his intention to resign as a result of disputes with fellow ministers, particularly Commerce Secretary
Guillermo Moreno. He denied he would resign; but there was nevertheless continued speculation on his resignation or replacement in the wake of the agrarian crisis. Lousteau resigned on 24 April 2008, with the tax agency chief
Carlos Fernández replacing him. According to
The Wall Street Journal, his brief tenure was clouded from the outset by interference from former President
Néstor Kirchner's allies. Lousteau's policy initiatives often seemed to be eclipsed by those of Commerce Secretary Guillermo Moreno, a Kirchner loyalist described as "the administration's price policeman." ==Later work==