•
Adam Clayton Powell Sr. (1865–1953), minister of the Abyssinian Baptist Church in Harlem, New York •
Adam Clayton Powell Jr. (1908–1972), minister and politician, first African American to become a powerful figure in the United States Congress •
Alfred Hoare Powell (1865–1960), English Arts and Crafts architect, pottery decorator and artist •
Annie Powell (1906-1986) Welsh Communist politician •
Anthony Powell (1905–2000), English novelist •
Art Powell (wide receiver) (1937–2015), American football player, brother of Charlie Powell •
Arthur William Baden Powell (1901–1987), New Zealand malacologist and paleontologist •
Baden Powell (mathematician) (1796–1860), English mathematician; father of Robert Baden-Powell •
Bill Powell (1916–2009), American golf course designer •
Billy Powell (1952–2009), keyboardist of the American band Lynyrd Skynyrd •
Brian Powell (baseball player) (1973–2009), American baseball player •
Bud Powell (1924–1966), American jazz pianist and composer •
Caroline Amelia Powell (1852–1935), Irish-born American engraver and illustrator •
Cecil Frank Powell (1903–1969), British physicist and Nobel laureate in physics •
Charlie Powell (1932–2014), American football player, brother of Art Powell •
Colin Powell (1937–2021), United States Secretary of State, Chairman of the Joint Chiefs of Staff •
Cozy Powell (1947–1998), English drummer for the bands Black Sabbath, Rainbow, and Whitesnake •
Cynthia Lennon née Powell (1939–2015), British first wife of John Lennon •
Dawn Powell (1896–1965), American writer of satirical novels and stories •
Dick Powell (1904–1963), American singer, actor, producer, and director •
Dilys Powell (1901–1995), British journalist, author, and film critic •
E. Alexander Powell (1879–1957), American war correspondent and author •
Eileen Louisa Powell (1913–1997), Australian trade unionist and women's activist •
Eleanor Powell (1912–1982), American actress and dancer •
Elkan Harrison Powell (1888–1966), American publisher •
Enoch Powell (1912–1998), British politician •
Ernest Powell (1861–1928), English cricketer •
F. M. Powell (1848-1903), American physician •
Felix Powell (1878–1942), Welsh songwriter •
Francis Powell (priest) (1909–1998), dean of Belize •
Sir Francis Powell, 1st Baronet (1827–1911), English politician •
Frank Powell (1877–?), Canadian stage and silent film actor, screenwriter, and director •
Frank Powell (footballer) (1883–1946), English football manager •
Frank John Powell (1891–1971), British Liberal Party politician and magistrate •
Foster Powell (1734–1793) English long-distance walker •
Frederick Powell (1895–1992), British Royal Air Force pilot •
George Henry Powell (1880–1951), Welsh songwriter •
Gwyneth Powell (1946–2022), English actress •
Israel Wood Powell (1801–1852), Canadian politician in Ontario •
Israel Wood Powell (1836–1915), Canadian politician in British Columbia •
Ivor Powell (1916–2012), Welsh footballer •
Jackie Powell (1871–1955), South African rugby player •
Jaime Powell (1953–2016), Argentine paleontologist •
James Powell and Sons, English glassworkers •
Jane Powell (1929–2021), American actress, singer, and dancer •
Jay Powell (politician) (1952–2019), American lawyer and politician •
Jesse Powell (1971–2022), American R&B singer •
Jim Powell (British novelist) (1949–2023), British novelist •
Jody Powell (1943–2009), White House press secretary for Jimmy Carter •
John Wesley Powell (1834–1902), American soldier, geologist, and explorer of the American West •
Julie Powell (1973–2022), American food writer and memoirist •
Lange Powell (1886–1938), Australian architect and Freemason, designer of the Masonic Temple in Brisbane •
Lawrence Fitzroy Powell (1881–1975), British librarian and literary scholar •
Leslie Powell (1896–1961), British military officer and flying ace •
Leven Powell (1737–1810), American politician, soldier and planter •
Levin M. Powell (1798–1885), American naval officer •
Lewis Franklin Powell Jr. (1907–1998), Associate Justice of the Supreme Court of the United States •
Lewis Thornton Powell (1844–1865), Confederate soldier, hanged as a conspirator in the Lincoln assassination •
Lewis W. Powell (1882–1942), American politician and lawyer •
Mel Powell (1923–1998), American jazz pianist and composer •
Michael Powell (1905–1990), British film director •
Michael J. D. Powell (1936–2015), British mathematician •
Paul Powell (director) (1881–1944), American journalist, director, producer, screenwriter and actor •
Paul Warner Powell (1978–2010), American murderer convicted for the murder of Stacie Reed •
Philip Powell (architect) (1921–2003), British architect •
Ray Edwin Powell (1887–1973), Canadian businessman (founder of Alcan Aluminium) and educator (Chancellor of McGill University) •
Robert Baden-Powell, 1st Baron Baden-Powell (1857–1941), British Army lieutenant-general; founder of the world Scouting Movement •
Robert E. Powell (1923–1997), mayor of Monroe, Louisiana, 1979 to 1996 •
Roger Powell (1896–1990), English bookbinder •
Ron Powell (1929–1992), Welsh goalkeeper who played for Chesterfield •
Sam Powell (footballer) (1899–1961), English footballer •
Sandy Powell (comedian) (1900–1982), English comedian best known for his radio work of the 1930s •
Seth Powell (1862–1945), Wales international footballer •
T. G. E. Powell (1916–1975), British archaeologist •
Theresa A. Powell (1952–2023), academic administrator •
Thomas Powell (botanist) (1809–1897), British missionary to Samoa and botanist •
Tommy Powell (Gaelic footballer) (1894–1964), Irish Gaelic footballer •
Tommy Powell (English footballer) (1925–1998), English footballer •
Tristram Powell (1940–2024), English television director, film director, writer and producer •
Vince Powell (1928–2009), British sitcom writer •
Wick Powell (1905–1973), Welsh international rugby union footballer •
Wickham Powell (1892–1961), Welsh international rugby union and rugby league footballer •
William Powell (1892–1984), American actor •
William G. Powell (1871–1955), Marine Corps Brevet Medal recipient ==Living==