Minor leagues McDermott was assigned to the Red Sox'
Double A affiliate, the
Scranton Red Sox of the Eastern League. He ended the season with a 16–6 record and a 3.29
ERA, with 136 strikeouts in 175 innings. On July 14, 1946, at the age of 17, McDermott threw a
no-hitter against the
Albany Senators, making him possibly the youngest pitcher to throw a no-hit game in the high minors. The following season, McDermott was promoted to Boston's Triple-A affiliate, the
Louisville Colonels, where he struggled with his control. Subsequently, he was sent back to
Scranton to work on his mechanics. In Scranton, he discovered his form, going 12–4 with four
shutouts for the rest of the season, averaging almost one strikeout per inning. During the playoffs, McDermott, threw his second minor league no-hitter. Playing at home against the
Utica Blue Sox, McDermott walked
Richie Ashburn in the ninth inning. Ashburn took second on a
fielders's choice and reached third on a
sacrifice fly. With two outs, the catcher called for a curve, but McDermott missed the sign and threw a fastball. The catcher, expecting a curve, failed to catch the ball as it went sailing past him. Ashburn scored the only run of the game to give Utica the victory and McDermott the no-hit loss.
Major leagues 's
"The Rookie", a picture based on McDermott making the Red Sox roster. Figuring prominently in the work, right of center, is "the rookie", who was actually Sherman Safford, a high school athlete in
Pittsfield, Massachusetts asked to model for the painting. McDermott made it onto the Red Sox roster for the beginning of the 1948 season, appearing in seven games during the first two months of the season, mostly in lopsided losses. In 23 innings, he had 16 strikeouts and 35 walks, thus was returned to Scranton for more seasoning. After the minor league season ended, he was recalled when the major league roster expanded for the playoff run. While with Scranton, McDermott threw his third career minor league no-hitter. After 1949 spring training, McDermott was assigned to the Louisville Colonels. On May 24, he struck out 20
St. Paul Saints to set a new
American Association record that was never broken (the American Association folded in 1962). Over the next four games after his 20 strikeout performance, he struck out 19, 18, 17 and 19 to set a record for the most strikeouts over a five-game period, 93. Under pressure from sports writers, Boston, which was already eleven games out of first place, brought up McDermott to help their ailing pitching staff. McDermott got his first big league win after
Ellis Kinder left the game in the first inning. McDermott pitched eight innings of shutout baseball before being lifted for a reliever. He finished the season with a 5–4 record and two shutouts. On May 29, 1952, McDermott faced 27 batters and fired a one-hitter to beat the
Washington Senators, 1–0, at Fenway Park.
Mel Hoderlein's fourth-inning single was the only Washington hit and he was thrown out while trying to stretch the hit into a double. His finest season came in 1953 when he went 18–10. The following year, he was traded to the Senators for
Jackie Jensen. He finished his career with a 69–69 record playing for several different teams. After he refused to sign with the Tigers for the 1959 season, the Tigers sold his contract to the
Dallas Eagles of the
Texas League, with whom he also refused to sign. Then
Bill Veeck, owner of the triple A
Miami Marlins of the
International League, signed him to pitch on the same staff as
Satchel Paige and
Virgil Trucks. While playing winter ball in
Cuba in 1959, McDermott's team was at bat when
Fidel Castro led the
26th of July Movement that overthrew the regime of
Fulgencio Batista. Several people on the field and in the stands were shot, including McDermott's teammate and future
Cincinnati Reds shortstop
Leo Cárdenas. McDermott was an excellent hitting pitcher in his 12-year major league career, posting a .252
batting average (156-for-619) with 71
runs, 9
home runs, 74
RBI and 52
bases on balls. He hit .364 for the Red Sox in 1950 and .301 in 1953. He recorded 12 RBI in 1950 and 13 RBI in 1953 and 10 RBI with the Senators in 1955. Before 1961, Detroit gave McDermott his unconditional release. He signed with the
St. Louis Cardinals as a free agent. After divorcing his first wife, McDermott met Linda Biggio, who would become his second wife. After being out late one night, he invited Linda to his room. The
hotel detective saw her dressed in a
Hawaiian
muumuu and said, "You can't bring that
hooker into your room!" McDermott punched the detective in the mouth and was subsequently released by the Cardinals. ==Post-playing career==