in 2013
Minor leagues Before the 2011 season,
Baseball America rated Sanó the third-best prospect in the Twins' minor league system. Sanó spent 2011 playing third base and shortstop for the
Elizabethton Twins, the Twins affiliate in the
Appalachian League, hitting .292 with 20 HR and 59 RBI. After the 2011 season Baseball America rated him the top prospect in the Appalachian League, the 18th-best prospect in all of baseball, and (agreeing with
Baseball Prospectus) the top Twins prospect. Sanó spent 2012 with the Class-A
Beloit Snappers of the
Midwest League, transitioning fully to third base. Meanwhile, general manager
Terry Ryan said that the team hoped to move Sanó closer to the major leagues quickly. Still, his developing defense and propensity for striking out had the Twins making sure not to rush his path through the minors. Sanó hit .258 with a .373
OBP, and led the Midwest League with 28 HR and 100 RBI. After the 2012 season, Baseball America rated Sanó the second-best prospect in the Midwest League and the top Twins prospect, and Baseball Prospectus rated him the second-best Twins prospect.
MLB.com rated him the 12th-best prospect in the game, as well as the top third-base prospect. Sanó began the 2013 season with the
Fort Myers Miracle of the
Class A-Advanced Florida State League. On June 9, 2013, Sanó and
Eddie Rosario were promoted to the
New Britain Rock Cats of the
Class AA Eastern League. Sanó compiled 35 home runs, 103 RBI, and a .280 batting average. At the end of the 2013 season,
MLB.com ranked him the third-best prospect in the league, and second in the Twins organization, behind only
Byron Buxton. The Twins invited Sanó to
spring training in 2014. During spring training he tore his
ulnar collateral ligament and required
Tommy John surgery. He missed the 2014 season in recovery. Sanó began the 2015 season with the
Chattanooga Lookouts of the Class AA
Southern League, and batted .274 with 15 home runs and 48 RBIs through the end of June.
Minnesota Twins Sanó made his major league debut on July 2, 2015, and went 1-for-4. He had his first RBI on July 3. His first home run came on July 7 against
Kevin Gausman. He was named AL Rookie of the Month for August 2015. Sanó finished third in the 2015 AL Rookie of the Year voting, behind winner
Carlos Correa and runner-up
Francisco Lindor. The Twins moved Sanó to right field before the 2016 season, after signing
Byung Ho Park to be the designated hitter and retaining incumbent third baseman
Trevor Plouffe. A hamstring strain sent Sanó to the injured list on June 1. The Twins moved Sanó back to his natural position of third base when he returned to the team a month later. He finished the 2016 season batting .236 with 25 home runs and 66 RBI over 116 games. On
Opening Day in 2017, Sanó homered and drew a bases loaded walk against the
Kansas City Royals, helping the Twins snap an eight game Opening Day losing streak. He was named an
MLB All-Star in 2017, and finished as the runner-up to
Aaron Judge in the Home Run Derby. During the
All-Star Game, Sanó had an RBI single against
Alex Wood. He finished the 2017 season with 28 home runs and 77 RBI. The Twins made the postseason for the first time since 2010, but Sanó was left off the playoff roster with a shin injury. After a slow start to the 2018 season, Sanó was demoted to Fort Myers on June 14. He was batting just .203 with a .270 on-base percentage at the time of his demotion. He rejoined the Twins on July 28 after
Eduardo Escobar was traded to the
Arizona Diamondbacks. Sanó finished the season batting .199 with 13 home runs and 41 RBI in 71 games. He made his season debut against the
Seattle Mariners on May 16, hitting two doubles and driving in a run. Sanó launched a pinch hit walk-off home run against the
Atlanta Braves on August 5. He finished the 2019 season with a career high 34 home runs, and the Twins won their first AL Central title since 2010. Sanó hit his first career postseason home run in game one of the 2019 ALDS. Sanó signed a three-year, $30 million contract with the Twins on January 14, 2020. The contract included a team option for the 2023 season. The Twins moved Sanó to first base after signing free agent third baseman
Josh Donaldson in the offseason. Sanó hit .204 with 13 home runs and 25 RBI during the COVID shortened 2020 season. He had the most strikeouts in the league, with an astonishing 90 strikeouts in 186 at-bats. He delivered a walk-off single against the
Detroit Tigers on April 26. Sanó was placed on the injured list with a torn meniscus in his left knee on May 3. He briefly returned on July 25, but was placed on the injured list again less than a week later. Sanó played in just 20 games during the 2022 season, batting .083 with one home run. The Twins declined Sanó’s contract option for the 2023 season on November 7, making him a free agent. On February 7, 2023, Sanó hosted a free agent workout for interested teams. However, he did not find a contract, and instead returned to the Dominican Republic, saying he would play winter ball.
Los Angeles Angels On January 23, 2024, Sanó signed a minor league contract with the
Los Angeles Angels. On March 26, it was announced that Sanó had made the Angels' Opening Day roster. In 28 games for the Angels, he batted .205/.295/.313 with two home runs and six RBI. On July 8, Sanó was
designated for assignment by Los Angeles. He was released by the Angels organization on July 13.
Chunichi Dragons On December 15, 2025, Sanó signed a one-year contract with the
Chunichi Dragons of
Nippon Professional Baseball. ==Personal life==