Early career Blanchfield fought under Fighting Championships and amassed a record of 1–0 prior to being signed by
Invicta Fighting Championships.
Invicta Fighting Championships Blanchfield made her Invicta debut on March 17, 2018, against Brittney Cloudy at
Invicta FC 30. She won the fight by split decision. Her next fight came on November 16, 2018, facing
Kay Hansen at
Invicta FC 32. She won the fight via majority decision. On February 15, 2019, Blanchfield faced
Tracy Cortez at
Invicta FC 34. She lost the fight via split decision. Blanchfield faced Gabriella Gulfin on June 4, 2019 at Cage Fury Fighting Championships 76. She won the fight via submission in round one. On February 7, 2020, Blanchfield returned to Invicta, facing
Victoria Leonardo at
Invicta FC 39. In the second round Blanchfield dropped Leonardo with a head kick, finishing off the technical knockout victory with punches.
Ultimate Fighting Championship Blanchfield was expected to make her UFC debut as a short notice replacement for
Bea Malecki against
Norma Dumont on April 10, 2021 at
UFC on ABC: Vettori vs. Holland in a Bantamweight bout. In turn, the bout was pulled from the card by after Dumont missed weight by 3.5lbs. Blanchfield faced Sarah Alpar on September 18, 2021 at
UFC Fight Night: Smith vs. Spann. She won the fight via unanimous decision. Blanchfield was expected to face
Maycee Barber, replacing
Montana De La Rosa, on December 11, 2021 at
UFC 269. However, Barber withdrew in early November due to undisclosed reasons, and she was replaced by
Miranda Maverick. Blanchfield won the fight by unanimous decision. She furthermore set the women's flyweight single-fight takedown record, with eight total takedowns. Blanchfield faced
JJ Aldrich on June 4, 2022 at
UFC Fight Night 207. She won the bout via guillotine choke in the second round. Blanchfield faced
Molly McCann on November 12, 2022 at
UFC 281. She won the fight via a kimura submission in the first round. Blanchfield was scheduled to face
Taila Santos on February 18, 2023 at
UFC Fight Night 219. When the main event fight between Cory Sandhagen and Marlon Vera was rescheduled for another event, Blanchfield's fight against Santos was moved up to serve as the main event. Santos dropped out of the bout after her cornermen were denied visas into the United States, and was replaced by former
UFC Women's Strawweight Champion
Jéssica Andrade. Blanchfield won the fight via submission in round two. This win earned her the
Performance of the Night award. The match with
Taila Santos was rebooked and took place on August 26, 2023, at
UFC Fight Night 225. Blanchfield won the bout via unanimous decision. Blanchfield faced
Manon Fiorot on March 30, 2024, at
UFC on ESPN 54. She lost the fight via unanimous decision. Blanchfield faced former two-time
UFC Women's Strawweight Champion Rose Namajunas on November 2, 2024 in the main event at
UFC Fight Night 246. The bout was later shifted to the co-main event but remained five rounds. She won the fight by unanimous decision. Blanchfield was scheduled to face
Maycee Barber in the main event on May 31, 2025 at
UFC on ESPN 68. At the weigh-ins, Barber weighed in at 126.5 pounds, half a pound over the women's flyweight non-title fight limit. The bout was set to be at catchweight and Barber was to be fined 20 percent of her purse which was to go to Blanchfield. However, minutes before the walkouts were to take place, Barber had to withdraw due to a medical issue involving a seizure and the bout was cancelled. Blanchfield faced
Tracy Cortez in a rematch on November 15, 2025 at
UFC 322. She won the fight via a rear-naked choke submission in the second round. ==Personal life==