Minkhaung II was king of Ava from 1480 to 1501. His 20-year reign was the beginning of the decline of Ava's hold on Upper Burma. Yamethin, a region to the east of Ava, revolted upon Minkhaung's accession to the Ava throne and stayed independent throughout Minkhaung's reign. The southern regions of Prome and Tharrawaddy revolted in 1482, and also stayed independent. By the mid-1490s, the Shan states of Mohnyin, Mogaung, Momeik and Kale (Kalay) had also broken away, and begun raiding northern Ava territories. Minkhaung increasingly came to rely on Mingyi Nyo, the Viceroy of Toungoo, for military assistance. By the end of his reign, Toungoo was equally powerful as its nominal overlord Ava.