Brand was president of
Indiana University from 1994 through 2002; the school is a nine-campus institution of higher education with nearly 100,000 students, 17,000 employees and a budget of $3.4 billion. Brand oversaw the consolidation of the IU Medical Center Hospitals and Methodist Hospital to form
Clarian Health Partners in 1997. Also, under his leadership, the university's endowment quadrupled and it became a leader annually in terms of overall private-sector support. Brand may be best known for terminating men's head basketball coach
Bob Knight in 2000. Reactions to the firing were varied, with public opinion split with strong feelings one way or the other, common across the state. The night of the firing, a crowd estimated at 2,000, consisting mostly of students, vandalized the Showalter Fountain, the university football field and marched on the president's on-campus home, the Bryan House. During this unrest, Brand was hanged in
effigy but fundraising with alumni and donors reached record highs. Knight was replaced by IU's first hire of an African American coach, Coach Mike Davis, who led the team to the Final Four in 2002. One of his most notable and nationally acclaimed speeches was to the
National Press Club in 2001, entitled, 'Academics First: Reforming Intercollegiate Athletics'. He underscored the need for the academic community to acknowledge and address the disparities that exist between intercollegiate athletics and the true mission of higher education. On September 24, 2019, it was announced that the Informatics building on the IU-Bloomington campus would be re-named "Myles Brand Hall" in recognition of the "pathbreaking contributions that President Brand made to the academic core of this university". ==NCAA leadership==