In November 2005, Hyperion Books published Berkus's book ''Home Rules: Transform the Place You Live into a Place You'll Love'' (), a step-by-step guide to home design and decoration. In 2005, Berkus began selling his merchandise at
Linens 'n Things stores throughout North America. Berkus was the host of the short-lived reality show ''
Oprah's Big Give'', which premiered March 2, 2008, but the series ended on April 20 that same year. On May 13, 2008, it was announced by
ABC that it would not be renewed for a second season. On September 13, 2010, he debuted as the host of his own syndicated daily show,
The Nate Berkus Show, which was co-produced by
Harpo Productions and
Sony Pictures Television. It was recorded in Studio 42 at the
CBS Broadcast Center in New York, but aired in the nation's largest markets on the ten NBC-owned-and-operated stations. In December 2011, Sony Pictures decided not to renew
The Nate Berkus Show for a third season. Berkus is also an executive producer of the 2011 film
The Help. Berkus appeared as himself on the October 12, 2011, and October 13, 2011, episodes of
Days of Our Lives, a United States daytime television soap opera, designing the offices of MadWorld Cosmetics for
Madison James. His book
The Things That Matter was published October 16, 2012, by Spiegel & Grau. It became a
New York Times Best Seller and was named "One of the Best Interior Design Books of the Year" by the
Washington Post. In October 2012, Berkus collaborated with Target stores to launch his Target Home collection, a 150-piece line that includes bedding, bath, accessories, lighting, rugs, and window treatments. Since then he has released many different collections for season changes as well as holidays. He recently released a line of stationery and office essentials alongside his 2015 Cali-inspired spring collection. In January 2013, Berkus introduced his own fabric collection at Calico Corners. In March 2013, television journalists noted Berkus began working on a primetime series with NBC, initially titled
Renovation Nation. By May 2013 the title was changed to
American Dream Builders. Berkus was the host and one of the producers of the show in which, according to NBC, "American top designers, builders, architects and landscapers go head-to-head each week, putting their talents to the test on extreme home renovations." The show was not renewed after its first season. Alongside his husband, interior designer
Jeremiah Brent, he launched in 2017 the TV show
Nate & Jeremiah by Design broadcast on
TLC network. On August 30, 2017, it was announced that
Nate & Jeremiah by Design had been picked up for a second season. They have been on the
HGTV Show
The Nate and Jeremiah Home Project since 2021. In 2020, Berkus helped rebuild
Ellicott City, Maryland in
Gordon Ramsay's special. ==Personal life==