Breedlove was appointed by Trinity College president
John Carlisle Kilgo as the full-time librarian in September 1898. The library at that time consisted of some 11,000 volumes donated by faculty and literary societies, housed in a single room in the
Washington Duke Building. His first task was to catalog and classify the library's contents. In 1900, he studied library science under
William I. Fletcher at
Amherst College and also consulted with
Charles Ammi Cutter. and, as the collection grew, he labored to manage the flood of donations and purchases amid staff shortages. Breedlove was able to supplement his team of part-time student assistants with the hiring in 1914 of a full-time professional cataloger, Eva Earnshaw Malone, former librarian at
Meredith College. Opening in 1927, it held the entire collection until the completion of the
General Library in 1930 (renamed for William R. Perkins in 1966) on the new West Campus. The move to the General Library involved additional complexity as separate libraries were established for individual departments and schools including Biology, Chemistry, Divinity, Forestry, Law, and Medicine. The rapid growth "from an insignificant college collection to one of the great national libraries of the country" continued throughout the 1930s and 1940s with a million books and over two million manuscripts and other documents in the collection, managed by a staff of 70, at the end of his tenure. He returned to his librarian duties in 1943 during World War II until retiring again in 1946. Notable former members of his library staff included
Benjamin E. Powell,
William Porter Kellam,
Mortimer Taube, and
Lawrence Quincy Mumford. ==Later life and legacy==