The town's history dates to 1761, when local legislator Samuel Benton built a plantation home and called it "Oxford." The legislature ordered the area around his plantation to be the seat of Granville County. The town was not incorporated until 1816. The first
Masonic orphanage for children in the United States was built in Oxford. It was originally established as St. John's College in 1858. The college ceased operations shortly after opening, however. In 1872 the community decided that the property should be repurposed to educate disadvantaged populations. In December 1873 the first residents were admitted to the Oxford Orphans Asylum, which is today known as the "Masonic Home for Children at Oxford." In 1851 James H. Horner established
Horner Military School, which enrolled many young men from
New York,
Pennsylvania,
Virginia,
South Carolina and other states. Many of the students went on to become leaders in the United States government, such as
James Crawford Biggs,
Solicitor General under President Franklin D. Roosevelt at the inception of the
New Deal. After the barracks were destroyed by a fire in 1913, the school relocated to
Charlotte, North Carolina. The Oxford Female College was established in 1850 by North Carolina
Baptists. After suffering financial difficulties, the college was sold and became a private educational institution renamed "Oxford Female Seminary." In 1880 F. P. Hobgood took over leadership of the school, and it gained popularity under his leadership. The school closed in 1925, following Hobgood's death the previous year. In 1883 the state legislature established the
Colored Orphan Asylum in Oxford.
Henry Plummer Cheatham, a former U.S. congressman (1889-1893), was appointed as superintendent in the early 1900s and led the institution for 28 years. In 1970,
Henry Marrow was shot and killed in Oxford. The killing resulted in a racial protest. The events were chronicled by
Timothy Tyson in the book
Blood Done Sign My Name (2004) and a 2010 movie
with the same name. A
Confederate statue was erected in 1909 by the Granville Grays
United Daughters of the Confederacy at a cost of $3000.00 and valued in 2009 at $1,327,791.62. The monument was erected in the courthouse square facing away from the courthouse. The base, constructed of granite from
Warren County, is tall, and the bronze statue is tall. The monument, a memorial to the Confederate veterans of Granville County that served in the
Civil War in the Granville Grays Company D, 12th Regiment, was dedicated October 30, 1909. The statue had not arrived in time but the ceremony continued and the statue was placed at a later date. Following the 1970 Oxford protests, the city moved the monument from the courthouse square to a site in front of the Richard H. Thornton Library. Since 2009, some activists had suggested moving it to an historic graveyard located down the street. In June 2020 the statue was removed and is currently in storage. The
Central Orphanage,
Granville County Courthouse,
Joseph B. Littlejohn House,
Locust Lawn,
Oxford Historic District,
Paschall-Daniel House,
Archibald Taylor Plantation House, and
Thorndale are listed on the
National Register of Historic Places. ==Geography==