Isaacs left Natal in 1831, when Shaka's successor, half-brother, and assassin,
Dingane, was thought to be preparing to massacre the few Europeans living on the edge of his kingdom. In 1844 Isaacs abandoned his claim to the land granted him by Shaka and settled in Sierra Leone. From a base in Freetown, he built up a thriving business. Later, Isaacs purchased Matakong Island in today's Guinea and established a modern port, private army, and commercial base. He ruled Matakong with the consent of local kings and became a regional power-broker. However, in 1854 he was accused of slave-trading by Sierra Leone's governor, Sir
Arthur Kennedy. Isaacs got wind of his impending arrest thanks to an informant--the son of his Eurafrican lover--who worked in the Governor's own secretariat. Isaacs was able to flee Matakong and avoid arrest. He made his way back to England and there orchestrated a campaign to clear his name. When Kennedy was appointed Governor of New South Wales, Australia, and recalled to London, he took with him the sworn testimony relating to the slave-trading charges against Isaacs. The documents were lost when the ship in which he was travelling, the
Forerunner was wrecked off Madeira in October 1854. In the absence of the testimony, the English courts refused to proceed with the prosecution. Isaacs was free to return to operate his lucrative Matakong port. Later, Isaacs retired to Liverpool, where he was to spend the last years of his life with one of his daughters and her family. Isaacs died on 26 Jun 1872 in
Egremont, on the opposite side of the
Mersey from
Liverpool. His body was transported several hundred miles and buried in the
Canterbury Jewish Cemetery.{{cite web == Historians' commentary ==