Origins and designation In 1908, the
New York State Legislature created a system of unsigned
legislative routes across the state of
New York. Two of the routes created at this time were Route 7, which extended from the
Pennsylvania state line south of
Binghamton to
Albany via
Oneonta,
Cobleskill,
Berne, and
New Scotland, and Route 24, a highway extending from the east bank of the
Hudson River in
Rensselaer to the
Massachusetts state line near Mount Lebanon by way of Averill Park and
Nassau. In the vicinity of Rensselaer, Route 21 was routed on 3rd Avenue, 3rd Avenue Extension, North Greenbush Road, and West Sand Lake Road. When the first set of posted routes in New York were assigned in 1924, a highway connecting Route 21 in Averill Park to the Massachusetts state line at
Stephentown was designated as part of NY 7, a route that continued northwest from Averill Park to
Troy on modern
NY 66. By 1926, the portion of old legislative Route 7 from
Central Bridge to East Berne was designated as part of NY 43, a new route extending from Central Bridge to downtown Albany via East Berne, Clarksville, and
Delmar, while NY 7 was renumbered to NY 45.
Changes in routing In the
1930 renumbering of state highways in New York, NY 43 was truncated slightly on its western end to begin at a junction with the new
NY 30 north of
Schoharie. Meanwhile, NY 45 was reassigned to
another highway in
Orange County. The portion of former NY 45 from Troy to Averill Park became part of NY 66 while the remainder became an eastward extension of NY 43. The extended NY 43 was now
concurrent with
US 9 and
US 20 along Madison Avenue from Delaware Avenue to Rensselaer, where it followed Broadway and Washington Avenue to
US 4 in
Defreestville. The route continued east to Averill Park on what had been legislative Route 21. NY 43 was extended slightly following the construction of a new alignment for NY 30 near Central Bridge in the early 1940s. NY 30 now left its old alignment southeast of Central Bridge and bypassed the community to the east. The former routing of NY 30 into Central Bridge became an extension of NY 43, which overlapped NY 30 between the new alignment and Schoharie. When
NY 30A replaced
NY 148 in 1960, the short piece of NY 43 near Central Bridge became part of NY 30A and NY 43 was truncated back to NY 30 near Schoharie. In the late 1960s, NY 43 was rerouted through downtown Rensselaer to follow 3rd Avenue (previously
NY 381) east to US 4. From there, NY 43 overlapped US 4 northward to Defreestville, where it rejoined its previous alignment. NY 43 was truncated on its western end to the junction of 3rd Avenue and Broadway in downtown Rensselaer in the early 1970s, eliminating the overlap with US 9 and US 20 through Albany. Its former routing from Schoharie to Albany was renumbered to
NY 443. NY 43 remained on 3rd Avenue up to the late 1990s when it was rerouted to follow a new highway to
I-90 exit 8 west of Defreestville. The realignment eliminated the overlap with US 4 and also took NY 43 outside of the Rensselaer city limits for the first time since being extended across the
Hudson River in 1930. The former alignment of NY 43 along 3rd Avenue from Broadway to Barracks Road became part of
NY 151; ==Major intersections==