•
Carl Nickle (1914–1990), Canadian editor and publisher, oil baron and politician •
Don Nickles (born 1948), American politician, former Senator from Oklahoma •
Doug Nickle (born 1974), Major League Baseball relief pitcher •
Robert Nickle (1919–1980), American artist •
Robert Nickle (British Army officer) (1786–1855), major general, a commander of the forces in Australia •
Sonny Nickle (born 1969), English rugby league footballer •
William Folger Nickle (1869–1957), Canadian politician, father of William McAdam Nickle •
William McAdam Nickle (1897–1968), Canadian politician ==Fictional characters==