In 2010, Ali along with psychotherapist
Leyla Hussein founded
Daughters of Eve. The non-profit organisation was established to help young women and girls, with a focus on providing education and raising awareness on female genital mutilation. Ali co-founded
The Five Foundation, "The Global Partnership to End FGM", with Brendan Wynne in 2019. This non-profit organisation works to raise the issue of FGM on the international agenda and leverage funding for grassroots organisations working to end FGM. Ali previously worked as a civil servant. She also served as a women's rights activist and an independent training consultant for a number of years. Additionally, Ali served as a Network Coordinator for The Girl Generation. She has also written extensively on national gender rights. The book contained 42 stories from 152 interviews that Ali had undertaken with women across 14 countries. In
The Times, Hannah Betts described the book as "a compelling cross-cultural account of vaginal life". Isobel Shirlaw said in
i that it was an important book and that "The chorus of women's voices which provide a multi-dimensional, global view of these hidden issues is powerful".
The Guardian review by
Arifa Akbar praised the book as "rich collection of intimate and uncensored stories" and wrote that Ali "delivers the physicality of the women's experiences with all the leaking, faecal, bloody mess of the body laid bare", although noting that "deeper reflection is lacking" and criticising the omission of coverage of anyone that was not heterosexual and
cisgender. Ali told an interviewer from
The Guardian that: In 2020, Ali and
Mika Simmons co-founded the Ginsburg Women's Health Board, to campaign for a more effective and equitable healthcare system for women from the
National Health Service. The organisation is named after
Ruth Bader Ginsburg. In October 2020, then
Home Secretary of the United Kingdom
Priti Patel appointed Ali as an Independent Government Adviser for Tackling Violence Against Women and Girls. Ali was a direct appointment to the role, which, as is common with such roles, was not advertised. The role involves the formulation of a strategy to reduce violence against women and girls, with recommendations expected to be produced in 2021. Ali expressed her hope that the strategy would be a foundation to improve safety for women and girls through education and legislation, but that "whole system" change would be required to reduce violence. In December 2022 Ali said she does not want to serve under new Conservative Home Secretary
Suella Braverman and was on a "completely different planet" to Braverman on women's rights and ethnic minorities. ==Political activity==