From the beginning of the twentieth century, the shores of Haut-Nyong were reported as an epicentre of
sleeping sickness: in 1901 a German officer, Captain Von Stein, pointed out for the first time an outbreak of trypanosomiasis east of Atok, on the upper Nyong river. In January 1913, the German doctor
Philalethes Kuhn established the first Western medical establishment in Ayos. The 1920s saw new sanitary facilities constituting the logistical and scientific basis for the sleeping sickness control program led by the French military doctor Eugène Jamot, installed in Ayos in 1922, succeeding Dr Jojot. On 8 April 1926, a ministerial decreed established Jamot as the director of a mission to cure sleeping sickness, and at the end of 1926 the Centre d’Instruction d'Ayos was established under the direction of Doctor de Marqueissac. Between 1926 and 1931, the scourge of sleeping sickness was overcome in Cameroon. However, it is then recommended to continue the effort by financial means, sufficient staff and administrative autonomy. == Organisation ==