A text from year 8 of Ur III ruler
Shu-Sin (c. 2037–2028 BC) details a journey of 22 women from Eshnunna to Nippur and back via Upi with the Upi/Nippur leg in both directions being fully on water. A year name of the Old Babylonian ruler
Apil-Sin (c. 1767 to 1749 BC) read "Year Apil-Sin built (the city wall of) Upi" (mu u2-pi2-eki a-pil-den.zu ba-du3). Early in the reign of Old Babylonian Empire ruler Hamurabi, grandson of Apil-Sin, a conflict between Babylon, Mari, Eshnunna, and Elam resulted in Hamurabi being in control of the Upi area. A text from
Mari showed diplomacy over that area's disposition: From a text, it is known that the Kassite ruler
Burna-Buriash II (c. 1359–1333 BC) held an audience in Upi. A
Kudurru from the reign of
Adad-apla-iddina (c. 1064–1043) excavated at Assur is dated at Opis. In one of the annals of Neo-Assyrian ruler Sennacherib (705–681 BC) it states: The Neo-Babylonians dug the Nār-Šarri (later Nār-Nabû-kudurrī-uṣur) canal between the
Euphrates and the Tigris, which ended near Opis. The
Neo-Babylonian king
Nebuchadnezzar II (605–562 BC) built a long
wall between the two rivers to protect against a potential
Median invasion; the fortified line began at
Sippar and continued eastward beyond the Tigris and ended near Opis. In Nebuchadnezzar II year 40, 565 BC, a cuneiform document was written in Opis by a Judean trader, the first attestation of a Judean trader in Babylonia. In October 539 BC, the troops of the Babylonian king
Nabonidus (556–539 BC) defended Opis against the
Persians commanded by
Cyrus the Great (559–530 BC). The Babylonians were defeated and the native population revolted against its government. Without further fighting, Cyrus captured Babylon. Opis was located near the Persian
Royal Road, which connected the former
Elamite capital
Susa to the
Assyrian heartland around
Erbil and, further to the west, the
Lydian capital
Sardis. It is known that at the time of Nabonidus the city had a Šangû-Upia (“High-Priest-of-Opis”). In September 331 BC, the
Macedonian king
Alexander the Great (336–323 BC) defeated
Darius III of Persia (336–330 BC) at the
Battle of Gaugamela, and probably took possession of Opis about the same time as Babylon. A few years later, Alexander was forced by a mutiny at the
Hyphasis (now Beas) River to return from the long campaign in India, and his European troops revolted again at Opis (autumn 324 BC). In an attempt to craft a lasting harmony between his Macedonian and Persian subjects, he took an oath of unity before 9,000 Persian and Greek troops at Opis. In a similar vein, he had married
Stateira (the daughter of Darius) and celebrated a
mass marriage of his senior officers to Persian and other Eastern noblewomen at Susa just before coming to Opis.
Seleukos I Nikator (306–281 BC), one of Alexander's
Diadochi (Successors), founded the
Seleucid Empire and built his Mesopotamian capital
Seleukeia west of the river Tigris, some southwest of Opis. The
Hellenistic city of Seleukeia rapidly eclipsed older Mesopotamian centers in the region like Babylon,
Sippar, and Opis. In the 2nd century BC, the
Parthian Empire conquered the eastern provinces of the Seleucid Empire, including Seleukeia and Opis. Both cities were, in their turn, largely eclipsed by the emergence of the new Parthian (and subsequently
Persian) capital
Ktesiphon nearby, in-between Seleukeia and Opis. ==See also==