In the transitional government of Prime Minister
Ahmadou Cheiffou, appointed on 7 November 1991, Mahamadou was included as Minister of Mines, Energy, Industry, and Crafts. He was retained in his post in a cabinet reshuffle on 31 January 1993. Multiparty elections were held in February 1993, bringing the transition to an end; Mahamadou was not included in the government that was appointed on 23 April 1993. He served as Deputy Executive Secretary of the
Economic Community of West African States (ECOWAS) under the leadership of Executive Secretary
Édouard Benjamin from 1993 until 1998 and then worked as
Lutheran World Relief's Regional Representative for West Africa. After PNDS President
Mahamadou Issoufou won the
January–March 2011 presidential election and took office as President of Niger, Ouhoumoudou Mahamadou was appointed
Minister of Finance on 21 April 2011. Mahamadou served as Minister of Finance for a little less than a year; he was dismissed on 2 April 2012. Later the same month, he was appointed Director-General of Banque Internationale pour l’Afrique au Niger (BIA-Niger), a major bank. Mahamadou was appointed Director of the Cabinet of the President on 4 June 2015. After Issoufou was sworn in for a second term, he retained Mahamadou in his post as Director of the Cabinet of the President on 11 April 2016. == Prime minister ==