Bellinzona In December 2009, Kasami returned to Switzerland to play for
Bellinzona, signing a contract until 2011. He made his professional debut in March after his free transfer was cleared by
Swiss Football Association. Lazio terminated his contract after Kasami failed to appear on several training sessions in the youth teams or first team, and it was due to his indiscipline that Lazio did not want to buy his rights from Grasshopper.
Palermo On 7 June 2010, Palermo announced they had signed the midfielder in a five-year contract from Bellinzona. Despite his young age, he was immediately included in the first team and made his debut with a
rosanero jersey as a second-half substitute in the first leg of the
2010–11 UEFA Europa League play-off against
Maribor. He then made his Serie A debut later on 30 August, playing the entire home league game against
Cagliari, which ended in a 0–0 draw. He concluded the season with 24 appearances: 14 in the
league, 8 in
Europa League and 2 in
Coppa Italia. Zamparini hailed Kasami as "the new
Pastore".
Fulham On 25 July 2011, Kasami signed for
Fulham on a four-year deal for an undisclosed fee. He made his début for Fulham as a late substitute in the 0–0 draw in their
Europa League clash with
RNK Split. He was later in the starting line-up versus
Dnipro on 18 August 2011, playing for 88 minutes and was greatly involved in the set up of all the 3 goals. Kasami made his
Premier League début on 21 August 2011 against
Wolverhampton Wanderers at the
Molineux Stadium. Fulham lost the match 2–0. Kasami almost joined Pescara on loan on 1 January 2013, but the move could not be finalised in time due to a bad internet connection. Kasami joined
Luzern on loan until the end of the 2012–13 season on 15 February 2013. He made his debut in the 4–0 away defeat to
St. Gallen on 24 February 2013. He scored his first goal for Luzern in the 4–3 away victory over
Servette FC in the final game of the
2012–13 season on 1 June 2013. Following his loan spell with Luzern came to an end, Manager
Martin Jol revealed Kasami took a fifty per cent cut of his wage to stay at the club. He scored Fulham's first goal of the
2013–14 Premier League season in a 1–0 away victory against
Sunderland. Kasami then scored his second goal of the season against
Crystal Palace on 21 October; a dipping volley from the edge of the area, in a match that eventually ended a 4–1 away win to Fulham. This goal was nominated for the
FIFA Puskás Award for the best goal of the year, the only one nominated from the Premier League. A third was added with a deflected free kick in a 2–1 win at Norwich on 26 December 2013.
Olympiacos It was announced on 9 July 2014 that Kasami had signed for
Olympiacos for a fee of €5 million. On 23 August 2014, he netted his first goal in his official debut as a player of Olympiacos in a 3–1 home win against
Niki Volos. He scored again on 30 August 2014 against
Panetolikos in a 1–1 away draw. On 22 October 2014, Olympiacos pulled off one of the surprises of the
Champions League night when they beat
Juventus 1–0 in Piraeus with a first-half goal from Kasami. On 22 February 2015, Kasami experienced one of the most traumatic shocks in his life after the derby against
Panathinaikos. On 11 March 2015, Olympiakos's Portuguese coach
Vitor Pereira and Kasami were fined for their behavior after the team's
Greek Cup quarter-final 1–0 win over
AEK Athens. The disciplinary committee of the Greek soccer federation fined Pereira
€9,000 and Kasami was ordered to pay €7,000 for making gestures to the crowd which incited trouble. After a successful
2014–15, which ended with
double conquest, several reports in Italy are keep insisting that Kasami was likely to move to a
Serie A club and it is believed that
Fiorentina or
Inter were the most favourable destination. Despite serious interest from Fiorentina,
Bayer Leverkusen and lately from
Roma, Kasami did not complete his transfer on the deadline day. He scored his first goal for the
2015–16 season in a hammering 5–1 win against
PAS Giannina. On 2 October 2015, media source stated that Olympiacos' former manager Vitor Pereira and midfielder Kasami were prosecuted for provoking episodes in the Greek Cup semi final against AEK Athens. The Deputy Prosecutor Giorgos Lainis prosecuted Kasami and Vitor Pereira. Αt the same time, the Football prosecutor former Sports Prosecutor Konstantinos Simitzglou had begun preliminary examination by calling witnesses in order to combine his case with the prosecution. The two men were close to facing criminal responsibilities and even go to trial. On 9 June 2017, Kasami was sentenced to eight months in prison (on parole) for their behavior. The Swiss-Albanian international central midfielder were punished by the Greek Justice for offensively provoking the supporters of AEK after the end of
2014–15 Greek Cup quarter final (0–1) between the two teams in the
Olympic Stadium of Athens, after the lawsuit filed by the fan of home side, Christos Garifallou, and supported by their legal department.
Nottingham Forest On 3 August 2016, Kasami became Nottingham Forest's seventh signing of the summer when he joined the reds on a twelve-month loan deal from
Olympiacos. On 27 August 2016, he scored his first goal for the club in a 3–1 home win against
Leeds United. According to English sources, Kasami had expressed his wish to return to Olympiacos in January transfer window. The former Fulham star failed to hit the heights that were expected of him when brought to Nottingham by French manager
Philippe Montanier, who had since been sacked. On 14 February 2017, Kasami's half-volley gave Forest an early lead in a 3–2 away loss against
Fulham On 5 May 2017, Nottingham Forest announced that Kasami had returned to Olympiacos.
Sion On 31 August 2017, Kasami signed a three-year contract with Swiss club
FC Sion for an undisclosed fee. During the
2018–19 season Kasami scored eight goals and made three assists in 20 appearances for Sion and as a result became the subject of transfer interest from
Crystal Palace and Turkish club
Fenerbahçe as well as fellow Swiss team
FC Basel. On 20 March 2020,
FC Sion's president
Christian Constantin terminated the contracts of all players without notice after they failed to agree to an 80% salary pay cut during coronavirus pandemic. Players such as Pajtim Kasami,
Johan Djourou and
Alex Song among others, wished to secure themselves legally with lawyers before agreeing to sign.
Basel According to various news, Italian
Serie A club
Venezia F.C. had officially moved for the acquisition of the Swiss ex-international Kasami, however, the move never came into fruition. On 12 October 2020,
FC Basel announced that Kasami joined them on a two-year deal. Kasami joined Basel's first team for their
2020–21 season under head coach
Ciriaco Sforza. After playing in one test game Kasami played his domestic league debut for his new club in the away game in the
Kybunpark on 1 November 2020. He scored his first goal for the team in the same game, it was the last goal in the game, as Basel won 3–1 against
St. Gallen. He immediately became a regular starter, playing 32 games, scoring 12 in his first season. At the beginning of his second season with the club he was also regular starter under new head coach
Patrick Rahmen, but then after the winter break and following the change of trainer to
Guillermo Abascal, Kasami was used mainly as substitute. Kasami left Basel after his contract expired. During his period with the club Kasaim played a total of 92 games for Basel scoring a total of 23 goals. 65 of these games were in the
Swiss Super League, 1 in the
Swiss Cup, 13 in the
UEFA Europa Conference League and 13 were friendly games. He scored 16 goals in the domestic league, 2 in the Conference League and the other 4 were scored during the test games.
Sampdoria On 14 September 2023, Kasami signed a contract with
Sampdoria in Italy for one season. Kasami left Sampdoria by mutual consent on 3 February 2025.
Return to Sion On 11 February 2025,
FC Sion announced Kasami's return until summer 2026. His contract with Sion was terminated by mutual consent on 2 July 2025. In this half year, he made just nine appearances off the bench, totalling 112 minutes played. ==International career==