Main •
Kristen Bell (season 1) and
Emmy Raver-Lampman (season 2–3)
Recurring •
H. Jon Benjamin as Whitney Whitebottom, the
Mayor of New York City who is in league with Bitsy. He later resigns as mayor after Paige exposed him. •
Eugene Cordero as Brendan Brandenham, a boy that Molly secretly has a crush on and often flies his kite in the park. Molly fantasizes about him as her superhero partner Kite-Boy. He is the grand-nephew of Bitsy Brandenham and opposes her plan to buy Central Park upon learning about it. •
Rory O'Malley as Elwood, a park ranger and Owen's partner who always seems in over his head. He has a pet worm named Diane and has a natural rhythm. •
David Herman as Dmitiry (season 1), a
Russian oligarch that Bitsy hopes to get in league with. •
Brian Huskey as Doug, Paige's co-worker. •
Janelle James as Fran, another park ranger. •
Phil LaMarr as Randy, another park ranger. •
Tony Shalhoub as Marvin, Paige's boss. •
Fred Stoller as Leo Shallenhammer (season 1), a member of the City Council. •
Ed Asner as Ambrose Brandenham, Bitsy's older brother. •
Ester Dean as Hazel, Molly's friend and lab partner. In Molly's comic, her superhero counterpart is named "The Haze". •
Kerri Kenney-Silver as: • Lucy (season 2), a former maid whose employer left her everything in his will. • Dory Sterling (season 2), a hotel owner. • An unnamed member of the Park League (season 2). •
Marc Evan Jackson as Anton, Ambrose's butler. •
Stephanie Beatriz as Enrique, Cole's friend who shares his interest in the fantasy novel series
The Squirrel Quarrels. •
Amber Ruffin as Shauna, a friend of Hazel's from her basketball team that Molly gets jealous of. In Molly's comic, her superhero/supervillain counterpart is named "Sha-Boom".
Guest Introduced in season one •
Fred Armisen as • Esposito, a sanitation engineer manager. • Zoom Abromavich, a movie tour guide whose tours often involve obscure films or deleted scenes of films. •
Danny Burstein as Dick Flake, a fishing enthusiast. •
John Early as Augustus, Shampagne's dog therapist. •
Ron Funches as Danny, a boy who challenged Molly to chess. •
Christopher Jackson as Glorious Gary, a local skater in Central Park. •
Jessica Lowe as Anya, the wife of Zack and daughter of Dmitiry. •
Audra McDonald as Ashley, a likability consultant. •
Andrew Rannells as Griffin, another busker and the replacement narrator for the episode "Rival Busker" after Birdie previously gave away a spoiler to Paige. •
Robin Thede as Anita, an auditor that Bitsy hires to sabotage the park. •
Kelvin Yu as Sheng, another park ranger.
Introduced in season two •
Yvette Nicole Brown as Gina Tracker, the main character of the Tillermans' favorite
police procedural. •
Thomas Lennon as Leslie Portergrave, the owner of a hotel in Brooklyn. •
Norm Lewis as Lionel, a bartender at the Brandenham hotel. •
Keith David as Ward Wittlinger, Owen's idol. •
Patti LuPone as Roberta McCullough, the owner of ''What's New, New York?'', the newspaper where Paige works. •
Henry Winkler as Hank Zevansky, an insurance investigator. •
Gavin Creel as Young Hank. •
Catherine O'Hara as Gwendolyn Swish, the heiress to Swish Tassels who knocked Bitsy off the Annual 50 Women Over 50 Worth Over 50 Million list. •
Jenifer Lewis as Celeste, Owen's mother. ==Episodes==