Lefevere is from
Flanders, the Dutch-speaking region of the north and was a professional racer from 1976 to 1979, winning
Kuurne–Brussels–Kuurne and the fourth stage in the
Vuelta a España, both in 1978. When his sports career ended, Lefevere began a new enterprise as a
directeur sportif (team coach). In 1980, he was
directeur sportif at Marc Superia and then spent time at Capri Sonne (1981–1982). From 1985 to 1987, he was with
Lotto; in 1988 he joined Tvm and from 1989 until 1991 he was with Weinnman. From 1991 to 1994, Lefevere was one of the orchestrators behind team
MG-GB, with riders such as
Franco Ballerini and
Mario Cipollini. Lefevere became
directeur sportif of
Mapei in 1995, a team which was known for its success in one-day races. Riders included
Johan Museeuw and
Michele Bartoli. In 2001, Lefevere returned to Belgium and created
Domo-Farm Frites, with which he won several races, including two Paris–Roubaix (
Knaven, Museeuw). In 2001, Lefevere was declared cancer-free after being diagnosed with a pancreatic tumor in September 2000. A few months later, he resumed his role in Mapei. In July 2002, after the Mapei team announced it was withdrawing from racing, Lefevere joined with the owners of Quick-Step,
Frans De Cock, and the head of
Davitamon,
Marc Coucke, to announce the founding of team . The team changed denomination several times but always had Quick-Step as its primary sponsor. The formation became a point of reference in one-day races thanks to victories by
Paolo Bettini, twice World Champion, Olympic Champion and record victory holder in the Classics, along with
Tom Boonen, who made his mark more than a few times at the
Paris–Roubaix and in the
Tour of Flanders, won a World Championship and took home the green jersey in the 2007 Tour. In the early years of 2000, the team could also count on
Richard Virenque who, as part of the team, became the record-man for victories when it came to the polka dot jersey for best climber (7 times). In October 2010, Lefevere formed a joint venture with the Czech businessman
Zdeněk Bakala, who became the owner of the team. After a transitional 2011, in 2012 the team became , with Lefevere as CEO. In 2012, the team won 60 official victories, including Paris–Roubaix, the Tour of Flanders and the first edition of the World Championship Team Time Trials, 9 national titles, and the World Championship Time Trial with Tony Martin. In 2013, with the arrival of
Mark Cavendish, the team had more than 50 victories to its name, including five stages at the Giro d’Italia and four stages at the Tour de France. In 2014,
Michał Kwiatkowski of won the
rainbow jersey at the
2014 UCI World Road Race Championships in Ponferrada, Spain. On December 10, 2024, Lefevre announced that he would step down as director of the successful cycling team Soudal Quick-Step later that month. He will be succeeded by Jurgen Foré. ==Major results==