Atlanta Falcons Worrilow was signed as a
free agent after the
2013 NFL draft by the
Atlanta Falcons eventually making the final 53-man roster for the 2013 season. After spending a few weeks as the team's backup middle
linebacker, Worrilow moved into the starting strongside linebacker position. On a November 3, 2013, loss against the Carolina Panthers, Worrilow recorded a career-high 19 tackles, tying his previous week's performance and a franchise record for most tackles in a game since 1994. Worrilow ended the 2013 NFL season as the Falcons' leading tackler, landing him a spot on
Mel Kiper, Jr.'s All-Rookie Team alongside teammate and fellow rookie
Desmond Trufant. Worrilow ended the 2014 NFL season again leading the Falcons in tackles at 143 tackles (84 solo), two sacks, two forced fumbles, three passes deflected. In February 2014, Worrilow received the John J. Brady Delaware Athlete of the Year Award from the Delaware Sportswriters and Broadcasters Association. Worrilow ended the 2015 NFL season again leading the Falcons in tackles at 95 tackles (67 solo), one forced fumble, one fumble recovery, two interceptions, four passes deflected. In the 2016 season, Worrilow and the Falcons reached
Super Bowl LI, where they faced the
New England Patriots on February 5, 2017. In the Super Bowl, the Falcons fell in a 34–28 overtime defeat.
Detroit Lions On March 10, 2017, Worrilow signed with the
Detroit Lions. Worrilow recovered a muffed punt in a Week 17 matchup against the
Green Bay Packers.
Philadelphia Eagles On April 3, 2018, Worrilow signed with the
Philadelphia Eagles. On May 22, 2018, Worrilow tore his ACL on the first day of OTAs, ending his season. He was officially placed on injured reserve on June 13, 2018. On January 30, 2019, Worrilow signed a one-year contract extension with the Eagles. He was released by the Eagles on August 18, 2019.
Baltimore Ravens Worrilow signed with the
Baltimore Ravens on August 23, 2019. He requested his release from the team the next day to decide his future in the NFL. He worked out for the Eagles on September 10 and October 8, 2019, and for the
New York Jets on November 1, 2019.
New York Jets On November 5, 2019, Worrilow was signed by the
New York Jets. On September 16, 2020, Worrilow was signed to the
New York Jets practice squad, but was released on September 22, he then retired from his professional playing career. ==NFL career statistics==