Universidad San Martín Pedro Gallese began his youth career at Academia Tito Drago and Club Deportivo Junior FC before joining that academy at
Universidad San Martín in 2007. He made his way through the youth system and debuted for the senior team on 25 June 2008 in a 4–0 victory against
Atlético Minero. He made 63 appearances for the club and his performances earned him his first international call-up and eventual cap in 2014.
Loan to Atlético Minero With his first team opportunities limited, Pedro Gallese joined
Atlético Minero on loan for the 2009 season.
Juan Aurich In 2015, Pedro Gallese decided to leave Universidad San Martín after 7 years at the club. Gallese signed for Juan Aurich and made his debut for the team on 6 February 2015 in a 2–1 win over
Defensor La Bocana in the
2015 Torneo Descentralizado. Gallese played in the
Copa Libertadores for the first time on 19 February 2015, making his continental debut in a 3–0 defeat to
Tigres.
Veracruz Gallese's performances in the
Copa América Centenario in the United States in 2016 made him a target for several clubs. On 19 June 2016, Gallese eventually signed with Mexican club
Veracruz. He made his debut for the team on 10 July in the
2016 Supercopa MX, losing the match against
Guadalajara 2–0. In the first week of December 2019, Pedro Gallese was released by Veracruz after the club had been disaffiliated from Liga MX.
Loan to Alianza Lima After falling out of favor under Veracruz manager
Robert Siboldi the previous campaign, Gallese returned to Peru on a 12-month loan with
Alianza Lima for the 2019 season. He was also named Peruvian player of the year in 2019 and 2021.
Orlando City On 17 January 2020, Gallese joined
Major League Soccer team
Orlando City. He made his debut for the team in the season opener on 29 February, keeping a clean sheet in a 0–0 draw against
Real Salt Lake. On 31 July 2020, Gallese made the only save during a quarter-final
penalty shoot-out victory over
Los Angeles FC in the
MLS is Back Tournament. On 21 November 2020, Gallese was again involved in a penalty shoot-out as Orlando played their first
MLS playoff game in history against
New York City FC. Gallese appeared to successfully save the fifth penalty kick which would have won the match for Orlando but the play was overturned by
VAR and Gallese received a second yellow card for leaving his goal line early having already been booked in extra-time for time wasting. Ultimately Orlando won the match after defender
Rodrigo Schlegel replaced Gallese in goal and saved a penalty in the seventh round of the shootout. in February 2024 in May 2025In August 2021, Gallese was named an
MLS All-Star for the
2021 MLS All-Star Game. On 20 October 2022, Gallese was voted the winner of the 2022
MLS Save of the Year Award for stopping
Atlanta United's
Dom Dwyer's shot on goal on 17 July, resulting in a 1–1 draw. In December, Gallese signed a new contract with Orlando through 2024, with an additional option for the 2025 season. On 5 May 2025, Gallese was named to the
Team of the Matchday for his performance in a goalless draw against
Chicago Fire two days earlier. Gallese's clean sheet also meant that he extended the club record for the most consecutive clean sheets to five. Later the same month on 19 May, Gallese was once again named to the Team of the Matchday for securing a clean sheet and providing an assist on
Luis Muriel's opening goal in a 3–0 win at rivals
Inter Miami. On 28 July, Gallese was selected for the Team of the Matchday once again, this time for overcoming
Columbus Crew's
expected goal dominance as Orlando City defeated them 3–1 three days earlier. After the conclusion of the season, the team announced on 31 October that Gallese would be leaving at the end of his contract. Throughout his six season tenure at the team he became the most capped goalkeeper for the club and set club records for the most minutes played for a goalkeeper (18,188), most saves (568), wins (89), and clean sheets (57).
Deportivo Cali Gallese decided to move to
Colombia to continue his career at
Categoría Primera A club
Deportivo Cali, where he signed on 30 December 2025. Gallese made his debut on 18 January 2026 in the club's opening match, conceding a long distance shot to
Cristián Álvarez in a 1–0 loss at
Jaguares de Córdoba. ==International career==