•
Penelope Aitken (1910–2005), English socialite •
Penelope Aubin, English novelist •
Penelope Austin, Australian singer-songwriter •
Pénélope Bagieu (born 1982), French illustrator and comic designer •
Penelope Blackmore (born 1984), Australian rhythmic gymnast •
Penelope Blount, Countess of Devonshire (1562–1607), English noblewoman •
Penelope Boothby (1785–1791), English famous child model in British art •
Penelope Boston, American speleologist •
Penelope Bradshaw (died 1754?), British compiler of a cookery book •
Penelope Brothers, New Zealand chemistry academic •
Penelope Brown (born 1944), American anthropological linguist •
Penelope Carwardine, English painter •
Penelope Casas, American food writer •
Penelope Chetwode, English travel writer •
Penelope Coelen, South African beauty pageant contestant •
Penélope Cruz (born 1974), Spanish actress •
Penelope Delta (1874–1941), Greek author •
Penelope Dransart, Anthropologist, archaeologist, and historian •
Penelope Dudley-Ward (1914–1982), English actress •
Penelope Easton (1923–2020), American dietician, nutritionist, and educator •
Penelope Farmer (born 1939), English author •
Penelope Fillon (born 1955), wife of French politician and former Prime Minister of France
François Fillon •
Penelope Fitzgerald (1916–2000), Booker Prize-winning English novelist, poet, essayist and biographer •
Penelope Ford (born 1992), American professional wrestler •
Penelope Gilliatt (1932–1993), English novelist, short story writer, screenwriter and film critic •
Penelope Heyns (born 1974), South African swimmer and double gold medalist at the 1996 Olympic Games •
Penelope Hobhouse (born 1929), British garden writer, designer, lecturer and presenter •
Penelope Hocking (born 1999), American professional soccer player •
Penelope Houston (born 1958), American singer-songwriter •
Penelope Jencks (born 1936), American sculptor •
Penelope Keith (born 1940), English actress famous for TV sitcoms •
Penelope Lea, Norwegian climate activist •
Penelope Leach (born 1937), British psychologist •
Penelope Ligonier (1749–1827), English aristocrat and socialite •
Penelope Lively (born 1933), British fiction writer •
Penelope Maddy (born 1950), American philosopher •
Pénélope McQuade (born 1970), Canadian radio and television host •
Penélope Menchaca (born 1968), Mexican television host, singer, and actress •
Penelope Ann Miller (born 1964), American actress •
Penelope Mitchell (born 1991), Australian actress •
Penelope Mortimer (1918–1999), British journalist, biographer and novelist •
Penelope Mountbatten, Lady Ivar Mountbatten (born 1966), British philanthropist and businesswoman •
Penelope Niven (1939—2014), American academic and biographer •
Penelope Walton Rogers (1950–2023), British archaeologist •
Penelope Rosemont (born 1942), American visual artist, writer, publisher, and social activist •
Penelope Scott (born 2000), American musician, singer-songwriter, and producer •
Penelope Seidler (born 1938), Australian architect and accountant •
Penelope Spheeris (born 1945), American director, producer and screenwriter •
Penelope Stout (17th century), early white settler of Monmouth County, New Jersey •
Penelope Tree (born 1950), Anglo-American former fashion model prominent in swinging sixties London •
Penelope Trunk (born 1966), American writer and entrepreneur •
Penelope Wensley (born 1946), Governor of Queensland, Australia •
Penelope Wilton (born 1946), English actress •
Penelope Windust (1945–2022), American television, film, and stage actress == Fictional and mythological characters ==