The type specimen were collected near
Nequejahuira, Bolivia, at an altitude of .
Peperomia nequejahuirana is a
stoloniferous-erect herb with a somewhat simple
stem 2 mm thick, covered with fine short
hairs. The
leaves are commonly arranged about 4 at a node, elliptic-subovate, the lowest somewhat round and the uppermost sometimes somewhat oblong, obtuse, acute at base or cuneate, rather small at 1 × 1–2 cm or 1.5–2 × 2.5 cm. They are
hairless, 3-nerved with the
midrib branching, dull dark green above and paler beneath. The
petiole is 5 mm long and covered with fine short hairs. The
inflorescence is unknown. ==Taxonomy and naming==