Princess Sophie married her first cousin,
Charles Alexander, Hereditary Grand Duke of Saxe-Weimar-Eisenach, at
Kneuterdijk Palace in
The Hague on 8 October 1842. who married
Princess Pauline of Saxe-Weimar-Eisenach. •
Princess Marie Alexandrine of Saxe-Weimar-Eisenach (b. Weimar, 20 January 1849 – d. Trebschen, 6 May 1922), who married Prince Heinrich VII
Reuss. • Maria Anna Sophia Elisabeth Bernhardine Ida Auguste Helene of Saxe-Weimar-Eisenach (b. Weimar, 29 March 1851 – d. Weimar, 26 April 1859) •
Princess Elisabeth Sybille of Saxe-Weimar-Eisenach (b. Weimar, 28 February 1854 – d. Wiligrad, 10 July 1908), who married
Duke Johann Albrecht of Mecklenburg-Schwerin.
Catherine Radziwill, a contemporary of Sophie's, commented that, "...[Sophie] was very different from her husband, and, though extremely ugly, was a most imposing Princess. She was clever, too, and upheld the reputation of the Weimar family. She was a Princess of the Netherlands by birth...and kept and maintained at her court the traditions in which she had been reared. Notwithstanding her want of beauty, moreover, she presented a splendid figure, being always magnificently dressed and covered with wonderful jewels, among which shone a
parure of rubies and diamonds that were supposed to be the finest of their kind in Europe". In 1872, her sister-in-law,
Queen Sophie, wrote: The Grand Duchess of Weimar, Princess Sophie, is here. She is perfectly hideous, with such a smell you cannot come near her. Then, that small bundle of greasy fat imitates her mother’s ways and manners, which is extremely ridiculous, and I sit and listen as to the ghost of
Queen Anna, returned to tease and annoy.In 1885, Sophie became the sole heir to the
Goethe estate, after his last living descendant died. On 22 March 1897, Sophie fell ill with a cold, and died suddenly the following day from heart failure. ==Ancestry==