Main •
Mika Abdalla as McKeyla McAlister, the lead girl and an agent of NOV8. At the beginning of Part 4, she was given the name "The Owl". • Ysa Penarejo as Camryn Coyle, the engineer with a high IQ • Victoria Vida as Adrienne Attoms, the culinary chemist from Spain who always wears high heels •
Genneya Walton as Bryden Bandweth, the tech junkie of the group •
Antonio Marziale as Prince Xander (main: Part 1, recurring: Part 4) • Marcus Choi (main: Part 1) and Ash Lee (recurring: Part 5) as Charles Coyle, Camryn's father • Madeline Whitby as Jillian (Part 1) • Bernardo De Paula as Defector (Part 1) • Troy Fromin as George the Security Guard (Part 1) • Oliver Vaquer as Francois (Part 1) •
Danica McKellar as the Quail (Parts 1–2, 4–6), the group's chief intelligence agent in NOV8 and McKeyla's mother • Alyssa Lynch (main: Parts 2–4) and
Maddie Phillips (recurring: Part 5) as Devon D'Marco, an aspiring artist • Belle Shouse as Ember Evergreen (Parts 2–6)
Recurring • Jonathon Buckley as Henry (Part 1) • Melissa Mabie as A.D.I.S.N. (voice), McKeyla's talking notebook. Her name is short for "Advanced Digital Intelligence Spy Notebook". It is pronounced as "Addison". • Johanna Newmarch as Carson Lazarus (Parts 2–3) •
Ty Wood as Justin (Parts 2–3) • Maxwell Haynes as Kyle (Parts 2–6) •
Adrian Petriw as Retro (voice; Part 2) • Kurt Evans as Assistant Principal Wilson (Part 2) •
Vanessa Parise as the Falcon (Part 3), McKeyla's aunt Montana who is also a substitute for the Quail while she's off the grid •
Sarah Desjardins as Maddy McAlister (Parts 3–4, 6), McKeyla's big sister. At the beginning of Part 4, she was given the name "The Nighthawk". • Adam Beauchesne as Simon Temple (Part 3) • Emily Delahunty as Tessa (Part 5) • Houston Stevenson as Zach (Parts 5–6) •
Jody Thompson as Jenny Wallis (Part 5) • Catherine Haggquist as Dr. A. Crawford (Part 5) •
Richard Ian Cox as Professor Kato (Part 5) • Jay Hindle as Max McAlister (Part 6), McKeyla's father • Chris Rosamond as Bobby Stone (Part 6) • Loretta Walsh as Charlotte Adele (Part 6) == Episodes ==