Restrictions WHO comment: "Propyphenazone, a
pyrazolone derivative with
anti-inflammatory,
analgesic and
antipyretic activity, was introduced in 1951 for the treatment of
rheumatic disorders. As it is structurally related to aminophenazone it has been associated with severe blood dyscrasias. However, it cannot be transformed into potentially carcinogenic nitrosamines and has therefore been widely used as a replacement drug for
aminophenazone. In certain countries, products containing propyphenazone have now been restricted in their indications, whereas in others they are still available, sometimes as over-the-counter preparations." •
Sri Lanka •
Malaysia.Later, in the same month, based on extensive safety data submitted by Piramal, the Supreme Court of India stayed the centre's decision and allowed the sale of Saridon. Saridon was made available by
Piramal Enterprises Ltd. Commonly used to get relief from a headache, Saridon was available at ₹ 46.50 () per a strip which contained 10 tablets, marketed by
Bayer pharmaceuticals pvt ltd India. The formulation in India consisted of 150
mg of
propyphenazone, 250 mg of
paracetamol and 50 mg of
caffeine. Another medicine Dart commonly available also consists similar combination with 150
mg of
propyphenazone, 300 mg of
paracetamol and 50 mg of
caffeine.
Philippines Saridon is available in the
Philippines and is being sold at a suggested retail price of PhP4.35 per tablet. Initially available in the Visayas-Mindanao region only, it was rolled out in Luzon in 2011 with the goal of replicating its success in Visayas and Mindanao in a national scope. Saridon is the only pain medication in the country that has three active ingredients, and the only one listing caffeine as one of its ingredients.
Singapore Saridon is not found in the Singapore market anymore (valid 2016, 2019). In an old copy of DIMS, it was listed that it contained propyphenazone 150 mg,
ethoxybenzamide 250 mg,
pyrithyldione 50 mg, and caffeine 50 mg. Please look for an old reference to verify. == See also ==