Theoretical basis The theory behind the Purification Rundown is that toxins, drugs, and radioactive particles are stored in body fat, which are released through the exchange of fats (thus the oil consumption) and exercise, and then finally released via
perspiration and other normal mechanisms such as body waste. Independent scientific evaluations report that the concentration of toxins or drugs in the sweat is negligible, as they are primarily removed from the body through the liver, the kidneys and the lungs. Evidence offered has not demonstrated that detoxification is actually taking place. A 1995 review at a medical conference described the massive doses of niacin as inappropriate, especially since they cause the release of
histamine, which is counterproductive when dealing with chemical sensitivity. Psychologist Herman Staudenmayer describes the program as part of a trend for diagnosing and treating a
Multiple Chemical Sensitivity disorder which does not correspond to any known disease and is likely to be
psychophysiological. Three experts consulted by
The Buffalo News criticised the weak evidence and dubious assumptions behind the program.
David Emerson Root, a medical doctor affiliated with Narconon, has administered the program for twenty years and stands by the theory behind it. A non-Scientologist, he denies that the program collects money or new members for Scientology.
Newkirk Herald Journal editor Robert W. Lobsinger solicited a number of medical experts' opinions on the program in 1989. Dr. C. Mark Palmer of
Ponca City, Oklahoma rebutted the theory that sweating would clear out drugs, stating that "No matter how much a patient were made to sweat, it could not significantly increase his clearing of most drugs." After reviewing materials published by Narconon,
University of Oklahoma biochemistry professor Bruce Roe described the program as "a scam" based on "half-truths and pseudo-science." A report on Narconon for the
Department of Health in California described the mega-doses of vitamins as "hazardous" and "in some cases lethal". Prof. Michael Ryan, a
pharmacologist at
University College Dublin, testified in a 2003 court case that the program is scientifically unverified and medically unsafe. Those who market the program insist that it has been proven safe and effective. The marketing materials present
testimonials for its effectiveness. Some doctors who have observed the treatment have been impressed by the testimonials but asked for evidence that improvements are caused by the program itself rather than
suggestion,
delusion or the
placebo effect. In a 1999 French court case, five staff members of the Church of Scientology were convicted of
fraud for selling the program and other Scientology procedures. In Russia, the program has been banned by officials as a threat to public health. ==Adverse outcomes==