This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of
WD-repeat proteins. It is found among several proteins that binds directly to
retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. == Interactions ==