San Diego Chargers Caldwell was selected by the
San Diego Chargers in the second round of the
2002 NFL draft with the 48th overall pick. He played for the Chargers for four seasons from to . In his rookie season, he had twenty-two catches for 208 yards and three touchdowns and returned nine kickoffs for a 24.4-yard average. He returned to play a full season in
2005.
New England Patriots Caldwell subsequently signed with the
New England Patriots prior to the season. He went on to total over 60 catches and 700 yards on the season. During a playoff game against the Chargers, Caldwell had seven receptions for 80 yards, including a four-yard touchdown reception from
quarterback Tom Brady in the fourth quarter. A week later in the
AFC Championship game, he dropped two passes during the Patriots' 38–34 loss to the
Indianapolis Colts. Caldwell was released by the Patriots four days before the first game of the
2007 season.
Washington Redskins Caldwell signed a one-year contract with the
Washington Redskins in September 2007. During the season, he appeared in eight games for the Redskins with fifteen receptions for 141 yards. However, he was released during the final preseason roster cuts. In his six-season NFL career, Caldwell appeared in seventy-one games, starting in twenty-nine of them, while making 152 receptions for 1,851 yards and eleven touchdowns. He also tallied fourteen carries for 108 yards rushing. ==NFL career statistics==