Bowel resection

Types of enterectomy are named according to the relevant bowel segment: == Surgery ==

The anatomy and surgical technique for bowel resection varies based on the location of the removed segment and whether or not the surgery is due to malignancy. The below sections describe resection for non-malignant causes. Malignancy may require more extensive tissue resection beyond what is described here. Bowel resection may be done as an open surgery, with a long incision in the abdomen. It may also be done laparoscopically or robotically by creating several small incisions in the abdomen through which surgical instruments are inserted. Once the abdomen is accessed by one of these methods the surgery may proceed. Small bowel resection Once the abdomen is accessed, the surgeon "runs" the small bowel, viewing the entire small bowel from the ligament of treitz to the ileocecal valve. This allows for total evaluate of the small bowel to identify any and all pathologic sections. Once the area of concern is located, two small holes are created in the mesentery on either end of the segment. These holes are used to place a surgical stapler across the bowel and separate the segment of injured bowel from the healthy bowel on each end. Then bowel is then dissected away from the mesentery. Following this the remaining bowel is observed to verify continued blood flow. After resection the surgeon will create an anastomosis between the two ends of the bowel. Following this the hole in the mesentery created by removing the section of bowel is closed with sutures to prevent internal herniation. The resected section of bowel will then be removed from the abdomen and the abdomen closed. This concludes the procedure. Large bowel resection The right and left colon sit in the retroperitoneum. To access this space an incision is made along the line of Toldt. The colon is then mobilized from the retroperitoneum. Care is taken to avoid injury to the ureters and duodenum. The surgery then follows the same steps as small bowel resection. However, due to the colon's placement in the retroperitoneum, more dissection is often required to allow for tension free anastomosis. == Medical Indications ==

Cancer Small bowel or colon cancer may require surgical resection. Small bowel cancer often presents late in the course due to non-specific symptoms and has poor survival rates. Risk factors for small bowel cancer include genetically inherited polyposis syndromes, age over sixty years, and history of Crohn's or Celiac disease. Cases that present before stage IV show survival benefit from surgical resection with clear margins. It is recommended that surgical resection also include lymph node sampling of a minimum of 12 nodes with some groups extolling more extensive resection. When evaluation determines cancer to be stage IV, surgical intervention is no longer curative, and is only used for symptom relief. Due to its prevalence, screening protocols have been created for prevention of disease. Screening colonoscopies with or without polypectomy have been shown to decrease cancer morbidity and mortality. When cancer is more advanced and polypectomy is not possible surgical resection is necessary. Using imaging and pathologic evaluation of resected tissue the tumor may be staged using AJCC stages. In addition to surgery adjuvant chemotherapy may be used to decrease risk of recurrence. Chemotherapy is standard with stage III cancer, case dependant in stage II and palliative in stage IV. Diet high in processed food and sugary drinks has also been shown to increase recurrence of stage III colon cancer. Bowel obstruction Bowel obstructions are commonly secondary to adhesions, hernias, or cancer. Bowel obstruction can be an emergency requiring immediate surgery. Original testing and imaging include blood tests for electrolyte levels, and abdominal X-rays or CT scans. Treatment often begins with IV fluids to correct electrolyte imbalances. Obstructions may be complicated by ischemia or perforation of the bowel. These cases are surgical emergencies and often require bowel resection to remove the cause of obstruction. Adhesions are a common causes of obstruction, and frequently resolve without surgery. Other causes of bowel obstruction include volvulus, strictures, inflammation and intussusception. This is not an exhaustive list. Perforation Bowel perforation presents with abdominal pain, free air in the abdomen on standing X-ray, and sepsis. Depending on the cause and size, perforations may be medically or surgically managed. Some common causes of perforation are cancer, diverticulitis, and peptic ulcer disease. When caused by cancer, bowel perforation typically requires surgery, including resection of blood and lymph supply to the cancerous area when possible. When perforation is at the site of the tumor, the perforation may be contained in the tumor and self resolve without surgery. However, surgery may be required later for the malignancy itself. Perforation before the tumor usually requires immediate surgery due to release of fecal material into the abdomen and infection. Ischemia Bowel ischemia is caused by decreased or absent blood flow through the Celiac, Superior Mesenteric, and Inferior Mesenteric arteries or any combination thereof. Untreated acute mesenteric ischemia can cause bowel necrosis in the affected area. This requires emergent surgery as survival without endovascular or operative intervention is around 50%. Ischemic bowel injury often requires multiple surgeries days apart to allow bowel recovery and increase odds of successful anastomosis. == Complications ==

Anastomotic leaks/Dehiscence An anastomotic leak is a fault in the surgical connection between the two remaining sections of bowel after a resection is performed. This allows the bowel contents to leak into the abdomen. Anastomotic leaks may cause infection, abscess development, and organ failure if untreated. Surgical steps are taken to prevent leaks when possible. These include creating anastomoses with minimal tension on the connection and aligning the bowel to prevent twisting of the bowel at the anastomosis. However, it is believed that most leaks are caused by poor healing, not surgical technique. Risk factors for poor healing of anastomosis include obesity, diabetes mellitus, and smoking. Treatment of the leak includes antibiotics, placement of a drain near the leak or developing abscess, stenting of the anastomosis, surgical repair, or creating of an ileostomy or colostomy. Internal and incisional hernias Any abdominal surgery may result in an incisional hernia where the abdomen was accessed. Hernias develop when the fascia of the abdominal cavity separates after the surgical closure. This may be due to suture failure or poor wound healing. Other risk factors include obesity and smoking. Smaller closure stitches and the use of mesh when closing open surgeries may decrease the risk of hernia occurrence. However, the use of mesh is limited by the surgery performed and contamination or risk infection. When colon is resected hernias may form through the mesenteric defect. This is more common with gastric bypass surgery. Internal hernias may cause ischemia and require emergency surgery to resolve. Adhesions and post-op SBO/BO A common complication of all abdominal surgeries is adhesions. Adhesions are bands of scar tissue that form after surgery or injury to the abdomen. They can displace or obstruct areas of the bowel. Approximately 1 in 5 emergency surgeries are due to adhesive bowel obstruction. When possible this is managed without surgery with IV fluids, and NG tube to drain the stomach and intestines, and bowel rest (not eating) until the obstruction resolves. If signs of bowel ischemia or perforation are present then emergency surgery is required. Laparoscopic adhesiolysis is the most common surgery used when bowel rest and medical management fail to resolve the obstruction. The acute form lasts up to one month following bowel resection. Symptoms include diarrhea, malabsorption, and metabolic derangements. This is treated primarily by IV fluids and electrolyte replacement. Acute short bowel syndrome is followed by the adaptation phase which can last up to two years. During this time the small bowel slows movement of bowel contents to allow for more absorption. About half of all patients with short bowel syndrome progress to chronic disease. Chronic short bowel syndrome may require total parenteral nutrition and chronic central line use. These may cause complications such as bacteremia and sepsis. Other complications of short bowel syndrome are chronic diarrhea or high output from the ostomy site, intestinal failure associated liver disease, and electrolyte level abnormalities. ==See also==