Kissi-Debrah's campaign for clean air followed the death in 2013 of her nine-year-old daughter, Ella Roberta Adoo-Kissi-Debrah. Ella Roberta had experienced severe asthma attacks over several years, and campaigned for air pollution to be included on her child's
death certificate. Her campaign led to a second inquest in 2020, where evidence about air pollution was considered, with the Record of Inquest finding: "Died of asthma contributed to by excessive air pollution". The subsequent
Report to Prevent Future Deaths identified the
South Circular Road, London as the source of pollution. The finding was covered in the media at the time. In 2023 Great Ormond Street Hospital started to add average air pollution data for patient's postcodes their files so that this could be considered during diagnosis and treatment, while recognising that it may not be possible for patients to change where they live, work or play. In January 2024, Kissi-Debrah began High Court legal action against three British government departments in an attempt to establish a legal right to clean air. In October 2024, she received an undisclosed sum from the UK government in settlement of this action. Kissi-Debrah also co-founded the Ella Roberta Family Foundation to promote her goals more widely to the public and officials. This charity aims to improve the lives of children affected by asthma in South East London. It engages with politicians and policy makers as well as young people and communities to raise awareness of asthma, advocate for better medical treatment of asthma and also campaigns for clean air. Kissi-Debrah is the director. that aims to reduce air pollution from cars. In a 2020 interview with
The Observer, she said: "For people who live in an LTN, yes, life is better, I don't deny that, but their traffic is going somewhere. You cannot live in a neighbourhood where one part has an LTN and children are cycling and playing outside and the roads are safe, then pop along a couple of roads later and there's gridlocked traffic. We cannot live in a society like that." She was also a candidate in the
2021 London Assembly election for the
Green Party of England and Wales, finishing third in
Greenwich and Lewisham. She is a
World Health Organization advocate for health and air quality. ==Electoral history==