•
Adolfo Ruiz Cortines (1890–1973), President of Mexico 1952–1958 •
Alejandro R. Ruiz (1923–2009), U.S. Army recipient of Medal of Honor in World War II •
Alexandre Ruiz (born 1987), French rugby union referee • Andrés Ponce
'Andy' Ruiz Jr. (born 1989), American professional boxer of Mexican descent •
Antoñito Ruiz (born 1951), Spanish child actor and stuntman •
Ashley Ruiz (born 1976), American singer, prior member of the group Menudo •
Bartolomé Ruiz (1482–1532), Spanish conquistador •
Bernardo Ruiz (1925–2025), Spanish road bicycle racer •
Bernardo Ruiz (filmmaker), Mexican–American documentary filmmaker •
Blas Ruiz, Spanish explorer •
Brunilda Ruiz (1936–2019), American ballet dancer •
Bryan Ruiz (born 1985), Costa Rican football player •
Carlos Ruiz (disambiguation), several people •
Cesar Ruiz (disambiguation), several people •
Chela Ruiz (1921–1999), Argentine actress • Chris Ruiz, German electronic DJ and producer, member of band
And One • David Resendez Ruíz (unk) Mexican-American prison activist known for
Ruiz v. Estelle •
Edgar Humberto Ruiz (born 1971), Colombian road cyclist •
Emilio Ruiz Muñoz (1874-1936), Spanish priest and press pundit •
Enzo Ruiz (disambiguation), several people •
Estanislau Ruiz Ponsetti (1889–1967), Spanish engineer and socialist politician •
Estela Ruiz (born 1936), Mexican-American Marian visionary •
Esteury Ruiz (born 1999), Dominican baseball player •
Félix Ruiz (1940–1993), Spanish footballer •
Frankie Ruiz (1958–1998), Puerto Rican salsa singer •
Gabriel Ruiz (disambiguation), several people •
Gabrielle Ruiz (born 1983), American actress •
Gonzalo Ruiz de Toledo, Spanish aristocrat •
Héctor Ruiz (born 1945), Mexican-American businessman, CEO of AMD •
Hipólito Ruiz López (1754–1816), Spanish botanist whose standard author abbreviations is
Ruiz •
Iñaki Ruiz de Pinedo (born 1954), Spanish politician •
Israel Ruiz Jr. (born 1943), New York politician •
Iván Ruiz (born 1977), Cuban volleyball player •
Jaime Ruiz (disambiguation), several people •
Jesús Zueco Ruiz (1946–2025), Spanish politician •
John Ruiz a.k.a. "The Quiet Man" (born 1972), Puerto Rican boxing champion •
José Francisco Ruiz (1795–1840), Texas revolutionary and politician •
José Martínez Ruiz, pseudonym Azorin (1873–1967), Spanish poet and writer •
José Javier Pomés Ruiz (born 1952), Spanish politician and Member of the European Parliament •
José Ruiz (baseball) (born 1994), Venezuelan baseball player •
Juan Ruiz (1283–1350), Spanish priest and poet •
Juan Ruiz de Alarcón (1581–1639), dramatist from New Spain •
Katie Ruiz (born 1984), American artist •
Keibert Ruiz (born 1998), Venezuelan baseball player •
Lorenzo Ruiz (c. 1600–1637), Filipino saint •
Marcel Ruiz (footballer) (born 2000), Mexican professional footballer •
Marcel Ruiz (actor) (born 2003), American actor •
Mari-Jo P. Ruiz, Filipina mathematician •
María Lourdes Ruiz (1965–2025), Nicaraguan discus thrower and shot putter •
Maria Luisa Alanis Ruiz (born 1948), American academic and activist •
Martha Cecilia Ruiz (born 1972), Nicaraguan poet, writer, journalist and activist •
Matías Alonso Ruiz (born 1952), Spanish politician •
Don Miguel Ruiz (born 1952), Mexican author, shaman, and teacher of the Toltec tradition •
Norge Ruiz (born 1994), Cuban baseball player •
Óscar Ruiz (referee) (born 1969), Colombian football referee •
Pablo Ruiz y Picasso (1881–1973), Spanish painter, sculptor, printmaker, ceramicist, stage designer, poet and playwright •
Raúl Ruiz (disambiguation), several people •
Renata Ruiz (born 1984), Chilean model, 2005 Miss Universe contestant •
Renato Ruiz (born 1977), Mexican professional wrestler •
Richard Ruiz, Mexican football player •
Rio Ruiz (born 1994), American professional baseball player •
Rodrigo Ruiz (born 1972), Chilean football player •
Rosie Ruiz (1953–2019), woman who finished first in the 1980 Boston Marathon but was later found to have cheated by jumping in during the middle of the race •
Samuel Ruiz (1924–2011), Mexican bishop from the state of Chiapas •
Tracie Ruiz (born 1963), American synchronized swimmer •
Vincenzo Arangio-Ruiz (1884–1964), Italian politician == Places ==