Asfendiyarov, a descendant of
Abul Khair Khan, was born in
Tashkent, where his father worked as a military translator. Asfendiyarov graduated in 1912 from the St Petersburg Military Medical Academy. Serving as a medical doctor early in the war with Germany, he was taken prisoner in East Prussia in December 1914, and held in various concentration camps until December 1915, when he was able to return to St Petersburg via
Sweden, during a prisoner exchange organised by the International Red Cross. After the
February Revolution in 1917, he was elected to the
Bukhara regional soviet of workers' and soldiers' delegates. In 1918, he served with the Red Army in the war against the Emir of Bukhara. He joined the Communist Party (
Bolsheviks) in 1919. In 1919–1925, Asfendiyarov worked in the
Turkestan Autonomous Soviet Socialist Republic, as People's Commissar for Health, 1919–20, and 1923–24; and for Agriculture, 1921–22, and as a secretary of the Central Committee of the Turkestan Communist Party, and a member of the Central Asian bureau of the All-Russian Communist Party. == Academic career ==