The altarpiece was originally painted in Siena, and transported to Sansepolcro for to be placed in the church of
San Francesco. In October 1900 the
Berenson family purchased three panels created by Stefano di Giovanni. The Berensons' collection consisted of
St. Francis in Glory, flanked by the standing
Blessed Ranieri and
St. John the Baptist, which scholars determined are only a part of a complex altar which had now become scattered among twelve collections throughout Europe and North America. The fact that it was produced by a
Sienese artist in
Siena, and shipped to the
Tiber Valley town in late spring 1444 also speaks to Sassetta's fame in his time period.
Bernard Berenson bequeathed many of Sassetta's painting from his Florence Villa to
Harvard University, in what became the Center for Italian Renaissance Studies in
Florence. A 3D computer-assisted reconstruction of the altarpiece's surviving parts is featured in
Sassetta: The Borgo San Sepolcro Altarpiece, edited by Machtelt Israels and released in 2009. ==Controversy==