Reuben was educated at
Columbia University. He graduated from medical school at the
State University of New York at Buffalo in 1985 and undertook his anesthesiology residency at
Mount Sinai Medical Center in
New York City. Reuben fell under suspicion when Baystate conducted a routine audit in May 2008 which revealed that Reuben had not been given approval for two studies that he intended to present during the hospital's research week. On March 10, 2009 a Baystate spokeswoman announced that Reuben admitted to fabricating many of the data underlying his research. Reuben never conducted the clinical trials that he wrote about in 21 journal articles dating from at least 1996. Although Reuben often co-wrote papers with other researchers, Baystate found that the other researchers did not know about or participate in Reuben's studies, Reuben also wrote to the
Food and Drug Administration, urging the agency not to restrict the use of many of the painkillers he studied, citing his own data on their safety and effectiveness. "His findings had a huge impact on the field." He also described Reuben's actions as the biggest case of fraud in the history of anesthesiology. Fellow editor Paul White believed that Reuben's fraudulent studies may have actually harmed patients due to the sale of "billions of dollars' worth of drugs" that caused slower recovery times. Reuben's work had actually come under scrutiny as early as 2007, when several anesthesiologists noticed his studies never showed negative results. Greg Koski, former director of the
Office for Human Research Protections, said the fraud was unusual because Reuben was able to carry it on for almost 13 years without being caught by the
peer review process. All of Reuben's 21 fraudulent articles, as well as the article abstracts, are documented in the magazine
Healthcare Ledger. Tufts has since cut ties with Reuben, and his Massachusetts medical license was permanently revoked after a period in which he voluntarily agreed not to practice. == Sentencing ==