Effects of a sedentary work life or lifestyle can be either direct or indirect. One of the most prominent direct effect of a sedentary lifestyle is an increased
body mass index (BMI) leading to
obesity. In 2006,
Lawrence D. Frank co-authored a highly-cited (over 1,900 citations) article:
Many Pathways from Land Use to Health. They determined that a 5% increase in a community's
walkability index was associated with a 32.1% increase in time spent walking or biking and a .23-point reduction in BMI. A country-level study examining the global cost of disease and its associated risk factors identified obesity as a top-seven risk factor associated with attributable death and a top-eight risk factor associated with attributable disease burden. Obesity was a top-three risk factor for high-income countries. At least 300,000 premature deaths, and $90 billion in direct healthcare costs are caused by obesity and sedentary lifestyle per year in the US alone. The risk is higher among those that sit still more than per day. It is shown to be a risk factor on its own independent of hard exercise and
BMI. People that sit still more than per day have a higher risk than those that sit fewer than per day. However, those that exercise at least per week are as healthy as those that sit fewer than per day. Indirectly, an increased BMI due to a sedentary lifestyle can lead to decreased productivity and increased
absenteeism from necessary activities like work. A sedentary lifestyle contributes to or can be a risk factor for: •
Anxiety •
Cardiovascular disease •
Migraines •
Breast cancer •
Colon cancer •
Gout •
High blood pressure •
Lipid disorders •
Mortality in adults •
Obesity •
Osteoporosis •
Scoliosis •
Type 2 diabetes Brain function Extended periods of sitting reduce overall blood circulation. This diminished blood flow leads to reduced oxygen delivery to the brain (
cerebral hypoxia), impairing cognitive functions such as concentration and alertness. The brain relies heavily on a continuous supply of oxygen and glucose for optimal performance; decreased circulation hampers this supply, resulting in cognitive sluggishness and decreased mental sharpness.
Neck and shoulders Sitting, particularly with
poor posture, often involves craning the neck forward to look at screens or documents. Such
forward head posture puts excessive strain on the
cervical vertebrae, leading to
muscle tension and pain in the neck and shoulders. Over time, this can cause the cervical vertebrae to become misaligned permanently, leading to chronic neck pain and potential
nerve impingement.
Upper body and back (FSU). Approximately 70% of applied axial compression is transmitted by the
vertebral body and the
intervertebral discs, with the remaining 30% of the load being distributed through the
facet joints The
intervertebral discs, which act as cushions between the vertebrae, are subjected to constant pressure when sitting for prolonged periods. This compression can lead to
disc degeneration and
herniation. Additionally,
collagen, a primary structural protein in
tendons and
ligaments, tends to harden when not regularly stretched and mobilized, which leads to decreased
flexibility and increased risk of injury in the back.
Heart disease Physical inactivity reduces the efficiency of the cardiovascular system. Sluggish blood flow allows for the accumulation of
fatty acids and
lipids in the
blood vessels. These deposits can adhere to the vessel walls, forming plaques (
atherosclerosis), which eventually narrow the arteries and restrict blood flow. This condition increases the risk of
coronary artery disease and
heart attacks as the heart struggles to receive adequate oxygen and nutrients. One study found that interrupting sitting with 20 minutes of light-intensity walking each hour significantly reduced systolic and diastolic
blood pressure in healthy participants or 3 minutes of light intensity walking every 30 minutes.
Overproductive pancreas A sedentary lifestyle contributes to decreased muscle activity, which affects
glucose metabolism. Reduced muscle activity leads to lower
insulin sensitivity, prompting the
pancreas to produce more
insulin to maintain normal
blood glucose levels (
metabolic syndrome). Chronic overproduction of insulin can exhaust the pancreas and contribute to insulin resistance, a precursor to
type 2 diabetes.
Leg problems Prolonged sitting impedes
venous return from the legs to the heart, leading to
venous stasis (slow blood flow in the veins). This can cause fluid to pool in the
lower extremities, resulting in swelling (
edema) and
varicose veins. Also, sluggish blood flow increases the risk of
clot formation, potentially leading to
deep vein thrombosis (DVT), a condition where blood clots form in the deep veins, which can travel to the
lungs and cause a life-threatening
pulmonary embolism. ==Mitigation==