1995–2009 As host of the syndicated television programme,
Box-office, starting in 1995, During this time, in 2001, she gained an interest in
adult film production while recording for the programme at the
Hot d'Or adult film festival in
Cannes, France. It inspired her next venture,
Sex Shop, which she hosted from 2001 to 2005, and during that time conducted interviews with celebrities such as
Robin Williams and
Penélope Cruz. According to ''
Maclean's magazine, Sex Shop'' attracted almost half a million viewers (about six per cent of Quebec’s population) every Saturday night to watch a "mélange of interviews with men and women in the adult entertainment industry and the sex trade, faux-risqué documentaries on sex toys and swinger couples and scenes from soft-focus smut movies." With her then-boyfriend Marc Trudeau, Losique co-founded the
production company, Image Diffusion International (IDI) in 1995. A
mockumentary starring Losique,
Bimbo, followed in 2006. Other IDI productions include the talk show
3950 and
Pole Position Québec, a 2010 reality show which searched for the best stripper in Quebec.
2010–present IDI produced a 2010 documentary series,
Le bum, les belles et la brute, on the lifestyle of
Éric Grenier, a Quebecer who was described by
La Presse as the province's
Hugh Hefner. When asked by
La Presse about Grenier's support for the
Hells Angels biker gang and his connections to its members, Losique denied having knowledge about his background or connections before producing the series. Losique appeared on the talk show
Tout le monde en parle to promote her 2010 book,
Confessions Sauvages, which contains photographs of her with others in the countryside. Accused of "reducing women to sexual objects to make money" in a letter to
La Presse written by feminist , Losique criticized the remarks on an primetime live programme briefly after, explaining: "How many girls don't have access to education? Women's rights are still precarious in the world, so an attack like this makes me mad. We are lucky to express ourselves anyway we want." In 2017, partnerships with the companies
Hustler TV and
Marc Dorcel produced the channels
Hustler TV Canada and
Dorcel TV Canada, respectively, distributed by her company Vanessa Media. In 2017, the high-profile
sexual misconduct scandal centred on film producer
Harvey Weinstein triggered similar allegations of sexual misconduct against famous personalities, including Affleck for his conduct in a 2004 interview with Losique. Losique defended Affleck, saying that he had acted that way only for the interview, and she accused American media of using the interview to fuel the scandal. Losique said she had previously rejected Weinstein's advances at the
Toronto International Film Festival, during which he allegedly asked her to go to his room. She headlined the Zoofest&OFF-JFL event at
Zoofest 2018 for her comedy show
Les dessous d’Anne-Marie. == Personal life ==