Persic set out on her maiden voyage on 7 December 1899, as the
Boer War was underway by this time, she carried 500 troops for South Africa. The maiden voyage turned out to be a fiasco as the ship developed a major fault: cracks developed on her
rudder stock casting, which resulted in it breaking by the time she reached
Cape Town.
Persic had to remain at Cape Town until a replacement could be shipped out from
Belfast and fitted. When the voyage resumed early the next year,
Persic repatriated injured and sick Australian troops. Part of the September–November journey, Australian artists
Hugh Ramsay and
George Washington Lambert travelled on the
Persic from Sydney to London. Lambert became successful in London; Ramsay preferred Paris but had to return to Australia when his health failed. During 1901, the
Persic made at least three return journeys between England and Australia. In February 1901 the vessel transported 'one of Australia's greatest and most loved poets' and bush balladeers,
Will H. Ogilvie from Sydney, where he returned to Scotland. Artist G. W. Lambert who travelled the year before on the
Persic also served as an illustrator in Ogilvie's 1898 work
Fair girls and gray horses. In July 1901 described as a large steamer, the
Persic went from
Liverpool, to Cape Town, via
Adelaide and
Melbourne to reach
Sydney. The return journey saw her loaded with 1,200 tons of wheat (bound for England) as large general cargo. Her November 1901 journey from Liverpool via Cape Town saw a passenger manifest of 335 passengers being 15 bound for Adelaide, 113 for Melbourne, and 207 for Sydney. On board were invalided and time-expired Australian and New Zealand soldiers from the Boer War. Additional to over two-hundred passengers on her return journey leaving Australia for England also saw her well-laden with cargo: :She carries a very large and varied cargo, comprising amongst other lines 10,200 bales wool, 300 tons coconut oil, 160 casks tallow, 1467 ingots tin, 140 tons chrome ore, 120 bales sheepskins, 30 bales furskins, 16,130 carcasses of mutton and lamb, and 1200 boxes butter. The
Persic continued her return trips services through the 1900s and 1910s. Mid-1910 saw the ship fitted with
wireless telegraphy. ==World War I service==