Roger Mills County SH-33 begins as
Texas State Highway 33 enters from
Hemphill County, Texas. At mile 4.2, it intersects
SH-30, which leads to
Erick. The highway runs alongside the
Black Kettle National Grassland to its intersection with
US-283 at mile 15.7. Turning southward, SH-33 overlaps US-283 to mile 16.9 at the community of
Roll, where
SH-47 joins the
concurrency. Together, the three routes pass through the National Grassland, and at mile 24.8, SH-33 turns to the east while US-283 and SH-47 continue south toward
Cheyenne. At mile 29.5, SH-33 passes
Strong City, and at mile 42.7 it passes the town of
Hammon with its intersection with
SH-34.
Custer County The intersection with SH-34 marks the county line. Mile 53.6 marks
Butler, and at 53.8
SH-44 runs out, which leads south to
Foss Lake, the town of
Foss, and later
Altus. At mile 66.2 SH-33 comes to
US-183, which leads south to
Clinton. SH-33 continues north concurrent with US-183 two miles (3 km) to mile 68.2, where US-183 continues northward to
Taloga and SH-33 turns east once again. At mile 72.6, the highway intersects
Custer City's Main Street before turning to the left. At mile 81.7 SH-33 enters Thomas at its second intersection with SH-47. At 83.8,
SH-54 ends, which leads to
Weatherford. At 87.0, SH-33 crosses the
South Canadian River, and at mile 90.1 SH-33 enters Dewey County.
Dewey County As SH-33 enters Dewey County, the
section line road on the county line can be followed a few hundred yards west to the unincorporated settlement of
Fay. After a mere in Dewey County, SH-33 enters Blaine County at mile 91.6.
Blaine County At mile 94.2, SH-33 reaches an intersection with
US-270,
US-281,
SH-3, and
SH-58. Here, SH-58 turns to the east, concurrent with US-270/SH-3 east and US-281 south. The roadway becomes four lanes at this point. At mile 101.3, the routes cross the
North Canadian River. At mile 103.8, the routes reach
Watonga and an intersection with
SH-8 north, which leads to
Roman Nose State Park. Here, US-270 and US-281 turn to the south toward
Hinton and
Red Rock Canyon State Park, and provide an alternate route to
Oklahoma City. Upon leaving Watonga, the SH-3/SH-33 roadway reduces to a three-lane arrangement. The two routes continue east to the Kingfisher County line at mile 115.7.
Kingfisher County Once SH-3/SH-33 have entered Kingfisher County, the road reduces to the conventional two lanes. At mile 131.5, the concurrency intersects
US-81 in downtown
Kingfisher. US-81 northbound goes to
Enid and
Wichita, whereas SH-3 diverges south onto US-81 southbound, which leads to
Okarche, where the two highways split to reach Okla. City and
El Reno respectively. This general vicinity is also the location of the crossing of the
Chisholm Trail. At mile 146.3, SH-33 intersects
SH-74F, which straddles the Logan County line south to Cashion.
Logan County SH-33's path through Logan County mostly parallels the
Cimarron River. At mile 152.0,
SH-74 intersects SH-33 with a four-way stop. Northbound SH-74 leads to
Crescent, and southbound SH-74 eventually becomes the
Lake Hefner Parkway in Oklahoma City. For the next few miles, SH-33 passes through the Cedar Valley golf course complex, and at mile 161.2 intersects
US-77 in downtown
Guthrie, Oklahoma's first capital. Near the east end of Guthrie, SH-33 once again becomes a four-lane highway before intersecting
I-35 at mile 162.9. At mile 163.1,
SH-105 to Tryon cuts off to the right as SH-33 turns to the left. The historic SH-33 turns off to the right at mile 169.2, although the old alignment is not marked other than a sign pointing to the town of
Langston. At mile 172.4 the driver may diverge from the highway to visit historic
Langston University, before the new alignment merges with the old alignment at mile 173.3. At this point, the highway narrows to two lanes. The old alignment quickly diverges into the town at
Coyle at mile 173.6, and the current roadway crosses the Cimarron River at mile 174.6.
Payne County The Cimarron River forms the county line, where the scar from an old steel truss bridge is visible just east of the highway. In 2005, a brand new concrete bridge was built west of the old one. Shortly into Payne County, the highway rejoins the old alignment at mile 175.5. At mile 185.1,
US-177 goes north to
Stillwater and overlaps SH-33 eastbound for one mile (1.6 km). At 186.1, it returns to a two lane highway, and US-177 diverges south into
Perkins and toward
Shawnee. As SH-33 continues east through Payne County, it crosses the Cimarron River again at mile 193.1 before intersecting
SH-108, which goes north to
Ripley, at 193.5. At mile 195.3,
SH-18 comes in from the south, and overlaps SH-33 into
Cushing, the "Pipeline Capital of the World." At mile 201.6, SH-18 diverges north toward
Pawnee. Upon exiting Cushing, SH-33 becomes a four-lane road forging eastward, and at mile 208.1 converges with
SH-99, whose south leg leads to
Stroud and
Ada. The SH-33/SH-99 concurrency continues east into Creek County.
Creek County Mile 209.8 is the county line, and shortly thereafter at mile 210.2, SH-33 Bypass provides a route for trucks to circumnavigate
Drumright to the north and west. At mile 211.9, on the east side of Drumright, SH-99 diverges to the north toward Pawhuska, and
SH-16 travels south toward
Muskogee.
SH-48 intersects SH-33 at mile 223.1, which goes south to
Bristow and north to
Cleveland. At mile 234.2 SH-33 intersects
I-44, which in this location is the
Turner Turnpike, a toll road to Oklahoma City and
Tulsa. Shortly thereafter, SH-33 ends after a tenure of at
SH-66. However, according to signage at the intersection, the highway actually turns northeast along SH-66 to downtown
Sapulpa, where it seemingly ends at the intersection of Main St and Dewey Ave, making the total length approximately . ==History==